Chief Bioprocessing Innovator

2 weeks ago


Boston, Massachusetts, United States EPM Scientific Full time
Job Summary:

The Chief Bioprocessing Innovator will spearhead the design, optimization, and scale-up of upstream processes for biologics production, focusing on cell culture and fermentation technologies. This pivotal role will be instrumental in developing robust, scalable, and cost-efficient processes for the development of novel biologic therapeutic products.

  • Foster a collaborative environment that promotes innovation, scientific excellence, and continuous improvement.
  • Establish clear objectives, KPIs, and development plans for team members.
  • Oversee the development and optimization of upstream processes, including cell culture, media development, bioreactor design, and process control strategies.
  • Collaborate with cross-functional teams to ensure seamless integration of upstream processes into the overall development pipeline.
  • Lead efforts in scaling up upstream processes from bench-scale to pilot- and manufacturing-scale, ensuring process consistency and robustness.
  • Troubleshoot and resolve scale-up challenges, ensuring alignment with quality and regulatory expectations.
  • Prepare regulatory submissions, and oversee the project lifecycle, from feasibility studies to full-scale production.

This is a hands-on leadership role with direct involvement in process development and close collaboration with downstream, analytical, and manufacturing teams. The ideal candidate will have extensive experience in bioreactor operations, cell line development, media optimization, and tech transfer, and a strong scientific background in cell culture, fermentation, and bioreactor operation.

Experience working with CDMOs and external manufacturing partners, as well as familiarity with automated process development tools and high-throughput screening technologies is desired.

The successful candidate will be a seasoned bioprocessing professional with a Master's or Ph.D. in Chemical Engineering, Biochemistry, Biotechnology, or a related field, and at least 5 years in a leadership role within the biopharmaceutical industry.


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