Manufacturing Supervisor

24 hours ago

San Diego, California, United States Poseida Therapeutics, Inc. Full time
Job Summary

The Manufacturing Supervisor - Cell Therapy will play a critical role in the development and manufacturing of cell therapies for cancer patients. This position will oversee the screening of donor blood products, isolation of primary lymphocytes, and production of CAR-T cells.

Key Responsibilities
  • Manage and work with the Healthy Donor Core team to screen donor blood products for possible enrollment into our preferred donor pool.
  • Oversee the isolation of primary lymphocytes for pre-clinical research, CAR-T cell production, and characterization of various products using flow cytometry and other in-vitro assays.
  • Schedule and manage direct reports, including research associates.
  • Conduct raw material testing and inventory management.
  • Coordinate with various departments on raw material inventory, CAR-T cell testing, in-vivo studies, data compilation, and Pan-T supply.
  • Ensure timely testing and documentation of blood product donor material.
  • Author and revise batch records, SOPs, worksheets, and other documents as necessary.
  • Partner with Process Development and Logistics to design and execute process improvement studies.
  • Compile accurate quarterly financial reports.
  • Communicate results and issues in a concise and timely manner to colleagues.
Requirements
  • Master's or Bachelor's degree in a scientific discipline with 5+ years relevant experience in the field of immunology, biology, or related field.
  • Self-motivated, positive, and detail-oriented with strong problem-solving and critical thinking skills.
  • Demonstrated ability to work effectively in a dynamic, cross-functional, and fast-paced team environment.
  • Expertise in cell culture and aseptic technique is required.
  • Proficiency in multi-parameter flow cytometry and FACS data analysis programs.
  • Experience with the characterization, culture, expansion, and manipulation of T cells or CAR-T cells.
  • Demonstrated experience with cell separation technologies (e.g. Miltenyi AutoMACS, Prodigy, etc.) is preferred.
  • Strong oral and written communication skills. Proficiency with MS-Office suite of software.
  • Excellent record-keeping and data management skills are required.
  • Ability to organize, communicate, and present data sets to key stakeholders from diverse backgrounds.
About Us

Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company utilizing our unique and proprietary genetic engineering platform technologies to create next-generation cell and gene therapies with the capacity to cure. We are passionate about making an impact on patients' lives with the development of our CAR-T therapies in various cancers and gene therapies for rare diseases.

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