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Senior Research Scientist/Associate Research Scientist/Research Scientist, Assay Development
2 months ago
Company Overview
Accellix is a leading provider of innovative solutions for the cell therapy industry. Our mission is to enable the development of safe and effective cell-based therapies by providing cutting-edge technology and expertise.
Job Summary
We are seeking a highly skilled and motivated Research Scientist to join our Assay Development team. The successful candidate will be responsible for developing and qualifying flow cytometry assay panels on our platform, collaborating with cross-functional teams, and providing analysis and feedback for developing automated analysis software.
Key Responsibilities
- Assay Development
- Develop and qualify flow cytometry assay panels on the Accellix platform, including optimization of formulations and protocols
- Collaborate with cross-functional teams while following design and development plans, executing assay verification and validation, and ensuring all assay requirements are satisfied
- Collaboration and Communication
- Provide analysis and feedback for developing automated analysis software
- Follow good manufacturing practices (GMP) in lab, clearly document experimental procedures and results, and assist team in maintaining inventory of lab supplies and reagents
- Participate in drafting and editing protocols for assay kit manufacturing and QC, and in tech transfer of new assays to the manufacturing team
- Present updates on projects and initiate brainstorming/troubleshooting discussions within the team and to external customer audiences
- Teamwork and Leadership
- Promote a strong working relationship with others in the lab, facilitate open communication, proactively identify and address issues, and support other team members to meet deadlines and manage shifting priorities
Requirements
- Education and Experience
- Senior Research Scientist: BS with 4+ years or MS with 2+ years, Associate Research Scientist: BS or MS with 8+ years, Research Scientist: PhD 0-2 years of relevant Industry experience
- Technical Skills
- Experience with experimental design and execution of flow cytometry assays, including antibody titrations, and optimizing and troubleshooting multicolor assays
- Experience with flow cytometry data analysis using FlowJo or similar analysis software
- Soft Skills
- Demonstrated ability to manage multiple projects, meet goals in a timely fashion, communicate delays and escalate challenges immediately
- Ability to design, execute, and analyze experiments with minimal oversight
- Ability to communicate effectively and collaborate within and across teams
Desired Qualifications
- Experience with generating and optimizing compensation matrices to address fluorescence spectral overlap in multiparametric flow data
- Familiarity with common biomarkers found on leukocytes, and/or familiarity with cell-based therapies and cellular engineering
- Experience with product development or instrument automation in an industry setting
- Experience with assay transfer to internal or external collaborators
- Experience with good documentation practices (GDP) and with drafting and reviewing documents such as SOPs and development reports
