Senior Principal Scientist

9 hours ago


Thousand Oaks, California, United States Amgen Full time
Job Description

Career Category: Research

At Amgen, our mission is to serve patients by developing innovative treatments. As a Senior Principal Scientist, you will play a crucial role in our research team, focusing on small molecule projects.

Key Responsibilities:

  • Serve as a project team representative and subject matter expert on the ADME/PK of small molecule therapeutics.
  • Leverage specialized ADME/PK skills to impact project progression and decision-making.
  • Plan and execute mechanistic ADME/PK analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics, and pharmacodynamics.
  • Contribute to the analysis of pre-clinical ADME and PK data for IND and NDA filings.

Requirements:

  • Doctorate degree in a relevant field and 3 years of experience, or Master's degree and 6 years of experience, or Bachelor's degree and 8 years of experience.
  • Strong background in pharmacokinetics, pharmaceutical sciences, or related fields.
  • Experience in supporting preclinical components of regulatory documentation.
  • Excellent interpersonal, technical, and communication skills.

What We Offer:

  • Comprehensive employee benefits package.
  • Discretionary annual bonus program.
  • Stock-based long-term incentives.
  • Award-winning time-off plans.


  • Thousand Oaks, California, United States Amgen SA Full time

    Senior Principal Scientist - PKDMAmgen is seeking a highly skilled Senior Principal Scientist to join our PKDM team. As a subject matter expert in ADME/PK, you will play a critical role in the development of small molecule therapeutic drug candidates.Key Responsibilities:Serve as a functional PKDM representative and subject matter expert on the ADME/PK of...


  • Thousand Oaks, California, United States Amgen Full time

    Job Title: Process Development Senior Principal Scientist – Peptide ChemistryAmgen is seeking a dedicated Process Development Senior Principal Scientist with industry experience in peptide synthesis and manufacturing to join our Drug Substance Technologies - Synthetics (DSTS) group in Cambridge, MA.Key Responsibilities:Lead a multidisciplinary project team...


  • Thousand Oaks, California, United States Amgen Full time

    Job Title: Process Development Principal ScientistAmgen is seeking a highly skilled Process Development Principal Scientist to join our team in Thousand Oaks, California or Cambridge, Massachusetts.Job Summary:We are looking for a talented scientist to lead the development of commercial manufacturing processes for small and hybrid molecules. As a Process...


  • Thousand Oaks, California, United States Amgen Full time

    Job Title: Process Development Principal ScientistAt Amgen, we are committed to serving patients by developing innovative treatments that improve lives. As a Process Development Principal Scientist, you will play a critical role in leading our team to achieve this mission.Job Summary:We are seeking a highly skilled and experienced Process Development...


  • Thousand Oaks, California, United States EPM Scientific Full time

    Job Title: Principal Scientist- Drug SubstanceJob Summary: We are seeking a highly skilled Principal Scientist to join our Manufacturing Sciences Department. The successful candidate will be responsible for leading cross-functional teams to perform process optimization, technology transfer, and investigations. The ideal candidate will have a strong...


  • Thousand Oaks, California, United States Takeda Pharmaceutical Company Ltd Full time

    Job Title: Principal Manufacturing ScientistThis role is part of the Manufacturing Sciences Department, specifically supporting Cell Culture and Purification manufacturing processes. As a Principal Manufacturing Scientist, you will oversee daily manufacturing support, inter-facility, and global process alignments/improvements initiatives of commercial and...


  • Thousand Oaks, California, United States Takeda Pharmaceutical Company Ltd Full time

    About the RoleThe Principal Manufacturing Scientist will support the Manufacturing Sciences Department in Cell Culture and Purification manufacturing processes. This role oversees daily manufacturing support, inter-facility, and global process alignments/improvements initiatives of commercial and clinical manufacturing operations of a multi-product...


  • Thousand Oaks, California, United States Takeda Pharmaceuticals Full time

    About the RoleWe are seeking a highly skilled Principal Manufacturing Scientist to join our Manufacturing Sciences Department. As a key member of our team, you will be responsible for supporting the development and implementation of manufacturing processes for our cell culture and purification operations.Key ResponsibilitiesLead technical and...


  • Thousand Oaks, California, United States Amgen Full time

    Job Title: Process Development Principal Scientist – Synthetic Peptides, Oligonucleotides, ADCsAmgen is seeking a highly skilled Process Development Principal Scientist to join our Drug Substance Technologies - Synthetics (DSTS) group. As a key member of our team, you will be responsible for developing efficient and sustainable manufacturing processes for...


  • Thousand Oaks, California, United States Takeda Pharmaceutical Company Ltd Full time

    About the RoleThe Principal Manufacturing Scientist will play a key role in supporting the Manufacturing Sciences (MS) Department, specifically in Cell Culture and Purification manufacturing processes. This position will oversee daily manufacturing support, inter-facility, and global process alignments/improvements initiatives of commercial and clinical...


  • Thousand Oaks, California, United States Amgen Full time

    About AmgenAt Amgen, we're dedicated to improving the quality of life for people around the world. We're a biotechnology company that discovers, develops, and delivers innovative medicines to treat serious diseases. Our mission is to serve patients, and we're committed to making a difference in the lives of those who need it most.Job SummaryWe're seeking a...


  • Thousand Oaks, California, United States Amgen Full time

    About the RoleAmgen is seeking a talented Process Development Senior Scientist to join our Drug Substance Technologies - Synthetics (DSTS) group. As a key member of our team, you will be responsible for inventing synthetic routes and developing safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances.Key...


  • Thousand Oaks, California, United States Amgen Full time

    Career Opportunity in Clinical PharmacologyAmgen is seeking a highly skilled Senior Clinical Pharmacology Scientist to join our team. As a key member of our clinical pharmacology group, you will be responsible for designing and implementing clinical pharmacology studies, analyzing data, and providing expert advice to cross-functional teams.Key...


  • Thousand Oaks, California, United States Aditi Consulting Full time

    Job Title: Associate Scientist/Cell Culture/Cell based/ELISALocation: Thousand Oaks, CADuration: 12 months contract with possible extensionJob Summary:We are seeking a highly motivated and experienced Associate Scientist to join our team at Aditi Consulting. The successful candidate will have a strong background in cell culture, molecular biology, and ELISA...


  • Thousand Oaks, California, United States Collabera Full time

    Job OverviewCollabera is seeking a highly skilled Associate Scientist to join our team in the field of life sciences. The successful candidate will be responsible for conducting cell culture and aseptic techniques, as well as performing ELISA and/or MSD assays. Key Responsibilities:Develop and execute cell culture protocols for primary cells and cell...

  • Senior Data Scientist

    7 hours ago


    Thousand Oaks, California, United States Amgen Full time

    Job SummaryAmgen is seeking a highly skilled Data Scientist to join our team in Cambridge, Massachusetts or Thousand Oaks, California. As a Data Scientist, you will be responsible for providing digital and lab informatics solutions to support the development of new treatments.Key ResponsibilitiesCollaborate with cross-functional teams to optimize lab...


  • Thousand Oaks, California, United States Innova Solutions Full time

    Associate Scientist OpportunityInnova Solutions is seeking a highly motivated and experienced Associate Scientist to join our team. As an Associate Scientist, you will play a key role in supporting our research and development efforts in the life sciences industry.Key Responsibilities:Conduct research and development activities in a laboratory settingDesign...


  • Thousand Oaks, California, United States AstrixTechnology LLC Full time

    Job OverviewAstrixTechnology LLC is seeking a highly skilled Senior Equipment Technician to join their team in Thousand Oaks, CA. As a key member of the biotech industry, our partner is a leader in delivering information technology consulting, regulatory advisory services, and staffing solutions to the scientific community.The ideal candidate will have a...


  • Thousand Oaks, California, United States Amgen SA Full time

    Transforming Lives through Innovative MedicineAt Amgen, we are dedicated to serving patients living with serious illnesses. Our mission drives us to research, manufacture, and deliver innovative medicines that help people live longer, fuller, and happier lives.Job SummaryWe are seeking a highly skilled Senior Principal Scientist to lead clinical pharmacology...


  • Thousand Oaks, California, United States Aditi Consulting Full time

    Job DescriptionThis role is responsible for creating and maintaining advanced analytics solutions using Spotfire and other data visualization tools. The Senior Business Intelligence Developer will work closely with cross-functional stakeholders to develop and implement data-driven insights that inform business decisions.The ideal candidate will have a strong...