Clinical Laboratory Specialist

4 days ago

Seattle, Washington, United States Adaptive Biotechnologies Full time
Job Title: Clinical Laboratory Technologist II

At Adaptive Biotechnologies, we're pushing the boundaries of immune medicine. Our mission is to harness the power of the adaptive immune system to revolutionize disease diagnosis and treatment.

As a Clinical Laboratory Technologist II, you'll play a critical role in our team's success. You'll be responsible for processing medically relevant biological samples through extraction and/or high-throughput next-generation DNA sequencing assays. This role requires attention to detail, clinical acumen, and a passion for innovation.

Key Responsibilities:
  • Perform DNA extractions, PCR amplification, or high-throughput sequencing assays on DNA libraries in accordance with standard laboratory processes and procedures.
  • Operate and maintain laboratory equipment such as liquid handling robotics and DNA sequencers.
  • Complete tasks as assigned (e.g., routine clinical or research sample processing, validations, reagent QC runs, or special projects) accurately and following strict methodologies.
  • Provide guidance to less-experienced staff.
  • Perform training and/or competency assessments for Clinical Laboratory Technician/Technologist team members on high-complexity molecular methods.
Complexity:
  • Perform protocols under compliance with regulatory agencies, models appropriate clinical, regulatory, and safety practices.
  • Suggest improvements to existing laboratory procedures and processes to improve the efficiency of the team.
  • Work on assignments requiring considerable clinical judgment and initiative.
  • Understand implications of their work performance and when to escalate issues upward.
  • Ensure compliance with lab regulatory agencies (GxP, FDA, ISO).
  • Keep accurate and detailed records for all workflows following Good Documentation Practices.
Knowledge/Level of Expertise:
  • Demonstrate excellent clinical judgment and integrity by possessing deep knowledge/skills in a range of laboratory procedures and processes.
  • Explain technical information within the team clearly and effectively.
  • Demonstrate understanding of underlying scientific principles of analytical methods and provide relevant information to Supervisor or Lead Technologist to assist with troubleshooting assay or instrument issues leading to appropriate corrective actions.
  • Exchange ideas and information effectively to Supervisor or Lead Technologist.
  • Handle sensitive information confidentially.
Interactions, Supervision, and Discretion:
  • Exhibit clear and effective communication to facilitate effective handoff procedures.
  • Provide guidance to more junior team members.
  • Follow standardized laboratory processes and procedures with little to no instruction on daily work.
  • Frequently exercise clinical discretion to suggest recommendations for improving work procedures and processes to improve efficiency.
Regulatory Responsibility:
  • Maintain continuing education credit requirements.
  • Record nonconformances for all appropriate errors.
  • Enter and track data in a laboratory information database (LIMS).
  • Operate and maintain laboratory equipment such as liquid handling robotics and DNA sequencers.
  • Regulatory responsibilities per Good Manufacturing Practices (GMP).
  • Regulatory responsibilities per Good Clinical Practices (GCP).
  • Regulatory responsibilities per Good Laboratory Practices (GLP).
  • Regulatory responsibilities of Testing Personnel for high-complexity testing as defined by 42CFR.
Position Requirements:
  • Bachelor's or higher in medical technology or laboratory science, chemical science, or biological science from an accredited institution.
  • Minimum of 1 year of experience and/or training in a clinical laboratory (holding a CLIA Certificate of Compliance/Accreditation) meeting the definition of high-complexity.
  • Minimum of 3 years of pertinent molecular laboratory experience.
  • Molecular biology skills (e.g., DNA Extraction, Purification, PCR, qPCR, next-generation DNA sequencing) and related technical knowledge.
  • Experience working with human specimens (e.g., blood, tissues, and/or cells) and biohazardous material.
  • Strong communication and interpersonal skills, ability to collaborate across teams and disciplines.
Preferred Qualifications:
  • ASCP(MB) certification.
  • Specialized knowledge and skills: Experience in a clinical, high-throughput environment is preferred.
  • Working knowledge of laboratory terminology, equipment, and supplies.
  • Competent in laboratory automation and demonstrated laboratory best practices.
  • Experience working within an electronic Laboratory Information Management System.
  • Self-motivated and can work independently, with minimal supervision, while also working as part of a team environment in a dynamic organization.
Working Conditions:

Job involves working in a laboratory handling human biological specimens. Flexibility and willingness to work more than standard hours when necessary, including late evenings & weekends.

Physical Requirements:

Individuals are required to sit or stand for much of the workday and perform data entry into computer systems.

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