Real World Evidence Associate Director
4 weeks ago
Job Summary:
The Real World Evidence Associate Director is a key member of the RWE team at Vertex Pharmaceuticals, responsible for leveraging expertise in epidemiology and real-world data to develop fit-for-purpose observational research. This role involves working cross-functionally to support the execution of observational research across the portfolio, with a focus on informing internal and external stakeholders on natural history and real-world outcomes within assigned therapeutic areas.
Key Responsibilities:
- Lead focused research on epidemiology of specific disease areas, including natural history of disease for business development and early development indications.
- Develop data sourcing strategies for early development and early clinical indications to support natural history of disease needed for regulators, payers, and clinicians.
- Execute evaluation of available registries and other data sources related to natural history and evidence to support clinical endpoints and inclusion/exclusion criteria.
- Determine potential use of RWE historical control within clinical development programs and feasibility of obtaining required data.
- Lead execution of approved research tactics within assigned indications.
- Develop draft protocol concepts and related materials for review and approval by internal scientific review boards.
- Align RWE research study tactics with functional and disease program goals, working closely with stakeholders.
- Contribute to development of performance metrics and dashboards for RWE projects.
- Represent RWE on relevant GMDA Sub-Teams, Program Teams, or Disease Strategy Teams where studies related to RWE are discussed.
- Represent RWE on cross-functional collaborations and working groups for pipeline products.
- Utilize strong oral communications skills and understanding of Vertex strategies to promote and translate RWD/RWE methods and activities across the company.
- Support and facilitate external research collaborations with key academic partners, consortia, and data vendors.
- Support the development of cross-functional evidence generation planning.
- Provide leadership and mentorship within RWE.
- Contribute to company publications strategy via development of conference abstracts, presentations, and peer-reviewed manuscripts based on RWE study findings.
Requirements:
- PhD (preferred) or MS/MPH in epidemiology, biostatistics, health economics and outcomes research, or similar required.
- Formal graduate training in Epidemiology/Health Services Research required.
- Minimum 5 years of experience working in observational research within the life sciences industry or relevant academic, government, or consulting environment.
- Minimum 3 years of experience working in RWE and/or Epidemiology at a biopharmaceutical company.
Flexibility:
This Hybrid-Eligible role offers the flexibility to work remotely up to two days per week or on-site with ad hoc flexibility. Vertex Pharmaceuticals is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law.
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