RNA Synthesis Associate Scientist II
4 days ago
We are seeking a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will design, synthesize, and purify oligonucleotides for research studies, and evaluate new chemical modifications for their use in the RNAi pathway.
Key Responsibilities- Design and develop novel synthetic methods and processes to expand the current capabilities of oligonucleotide synthesis.
- Analyze and interpret analytical data to present to team members and inform research decisions.
- Collaborate with team members to foster communication, efficiency, and culture, and effectively work in a highly interdisciplinary environment.
- Develop and implement new chromatographic methods, such as IEX/RP HPLC, SPE, and LC-MS, to improve the synthesis and purification of oligonucleotides.
- Utilize analytical instrumentation, such as UV-Vis spectroscopy, HPLC, and LC-MS, to analyze and characterize synthetic oligonucleotides.
- Bachelor's or Master's degree in Chemistry, Biochemistry, or a related field.
- 0-4 years of work experience, preferably in an industrial setting.
- Experience in solid-phase synthesis of biomolecules and a good understanding of the procedures involved in SPS.
- Experience with instrumentation such as HPLC, LC-MS, UV-Vis spectrometry, etc.
- Excellent written and oral communication skills, good organization skills, the ability to multitask, and the ability to work within a team and/or independently.
Alnylam Pharmaceuticals is a leader in the development of RNAi therapeutics, with a commitment to innovative science and a passion for excellence. Our culture is guided by core values of innovation, openness, urgency, excellence, and commitment to people. We are proud to be recognized as a top employer and a leader in the biopharmaceutical industry.
-
RNA Synthesis Associate
2 weeks ago
Cambridge, Massachusetts, United States Alnylam Pharmaceuticals Full timeJob Title: Associate Scientist II, RNA SynthesisJob SummaryWe are seeking a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will design, synthesize, and purify oligonucleotides for research studies, as well as evaluate new chemical modifications for their use...
-
RNA Synthesis Associate
5 days ago
Cambridge, Massachusetts, United States Alnylam Pharmaceuticals Full timeJob Title: Associate Scientist II, RNA SynthesisJob SummaryWe are seeking a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will design, synthesize, and purify oligonucleotides for research studies, as well as evaluate new chemical modifications for their use...
-
RNA Synthesis Associate
2 weeks ago
Cambridge, Massachusetts, United States Alnylam Pharmaceuticals Full timeJob Title: Associate Scientist II, RNA SynthesisThis role is considered On-Site.Job SummaryWe are seeking a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will design, synthesize, purify, and analyze chemically modified oligonucleotides.Key...
-
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob SummaryWe are seeking a highly skilled Senior Scientist to join our RNA Chemistry Team. The successful candidate will be responsible for the synthesis, purification, and characterization of oligonucleotides.Key Responsibilities:Design and implement oligonucleotide synthesis and purification protocols.Operate and maintain automated oligo synthesizers and...
-
Associate Scientist RNA Oligonucleotide Chemist
3 weeks ago
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob SummaryWe are seeking a highly skilled Associate Scientist to join our RNA Oligonucleotide Chemistry team. The successful candidate will be responsible for the identification, implementation, and fulfillment of synthesis, purification, and reaction scheme analytical characterization and method development of oligonucleotides.Key Responsibilities:Operate...
-
Senior Research Scientist, RNA Chemistry
1 month ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeAbout the RoleWe are seeking a highly skilled and experienced Senior Research Scientist to join our RNA Chemistry team at Sarepta Therapeutics. As a key member of our team, you will be responsible for designing and conducting novel oligonucleotide conjugates synthesis, purification, and characterization. You will also apply state-of-the-art delivery methods...
-
RNA Therapeutics Scientist
3 weeks ago
Cambridge, Massachusetts, United States Mindlance Full timeJob Title: Bench ScientistLocation: Cambridge, MA Duration: 18+ Months Job Description:At Mindlance, we are seeking a highly skilled Scientist to join our BioMedicine Design group (BMD) in the development of RNA therapeutic platforms. The ideal candidate will possess a strong background in RNA Biology and molecular biology techniques, with a proven track...
-
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob Title: Senior Research Associate/Associate Scientist, Nucleic Acid Process SciencesWe are seeking a highly skilled and motivated Senior Research Associate/Associate Scientist to join our Nucleic Acid Process Sciences team. This position will focus on building and executing processes to synthesize mRNA for our lead CRISPR/Cas9 gene editing programs.Key...
-
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob SummaryWe are seeking a highly skilled Research Associate to join our RNA Chemistry Team. The successful candidate will be responsible for the identification, implementation, and fulfillment of synthesis, purification, and reaction scheme analytical characterization and method development of oligonucleotides.Key ResponsibilitiesOperate and maintain...
-
Principal Scientist, Discovery Chemistry
2 weeks ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeAbout the RoleSarepta Therapeutics is seeking a highly skilled and experienced scientist to join our RNA Research group in Cambridge, MA. As a Principal Scientist, Discovery Chemistry, you will be responsible for designing and conducting novel oligonucleotide conjugates synthesis, purification, and characterization. You will also apply state-of-the-art...
-
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob OverviewWe are seeking a highly skilled Research Associate to join our RNA Chemistry Team. The successful candidate will be responsible for the synthesis, purification, and characterization of oligonucleotides.Key Responsibilities:Operate and maintain oligonucleotide synthesis platforms and other scientific equipment.Develop and implement oligonucleotide...
-
Principal Scientist, Discovery Chemistry
2 weeks ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeAbout the RoleSarepta Therapeutics is seeking a highly skilled and experienced scientist to join our dynamic and fast-paced chemistry team in Cambridge, MA. As a Principal Scientist, Discovery Chemistry, you will play a key role in our RNA research group, working on our PMO oligonucleotide platform and discovery research on improved delivery of...
-
Principal Scientist, Discovery Chemistry
1 month ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeAbout the RoleWe are seeking a highly skilled and experienced Principal Scientist to join our RNA Research group at Sarepta Therapeutics. As a key member of our dynamic and fast-paced chemistry team, you will be responsible for designing and conducting novel oligonucleotide conjugates synthesis, purification, and characterization. You will also apply...
-
Principal Scientist Upstream
3 weeks ago
Cambridge, Massachusetts, United States GSK LLP Full timeJob Title: Principal Scientist UpstreamGSK is seeking a highly motivated and experienced Principal Scientist Upstream to join our mRNA Drug Substance team in Cambridge, MA. As a key member of our team, you will play a critical role in shaping our mRNA vaccine platforms to accelerate the development of new vaccine candidates.Key Responsibilities:Design,...
-
Principal Scientist, Discovery Chemistry
4 weeks ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeUnlock the Potential of RNA TherapeuticsSarepta Therapeutics is at the forefront of genetic medicine, with a strong presence in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs). We're seeking a talented scientist to join our dynamic chemistry team in Cambridge, MA, to work on our PMO oligonucleotide platform and discovery...
-
Research Scientist
1 week ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeResearch Scientist 2Biological Engineering-Synthetic Biology Center-Weiss LabWe are seeking a highly skilled Research Scientist to join our interdisciplinary research lab. The successful candidate will contribute to the development of integrated biological systems capable of autonomously performing tasks related to therapeutic agents for various...
-
Scientist II, Advanced Technology Group
3 weeks ago
Cambridge, Massachusetts, United States Editas Medicine Full timeTransformative Therapies and Genetic InnovationEditas Medicine is at the forefront of genetic innovation, redefining healthcare through cutting-edge technologies. We're driven by a collective purpose to bring transformative and life-changing therapies to people living with serious diseases.As a Scientist II, Advanced Technology Group, you'll be part of our...
-
Scientist II, Advanced Technology Group
2 weeks ago
Cambridge, Massachusetts, United States Editas Medicine Full timeUnlock the Power of Gene EditingEditas Medicine is a pioneering company at the forefront of gene editing technology. We are seeking a highly skilled Scientist II, Advanced Technology Group to join our team and contribute to the development of novel gene editing technologies.About the Role:As a key member of our Editing Technology and Molecular Biology Team,...
-
Chemical Synthesis Specialist
4 days ago
Cambridge, Massachusetts, United States Atrium Staffing Full timeAbout Atrium Staffing: At Atrium Staffing, we're committed to providing exceptional talent to our clients. As a leading biomedical research institution, we're seeking a skilled Chemist to join our team.Client Overview: Our client is a renowned research institution dedicated to translating biological discoveries into innovative therapeutic strategies. They're...
-
Scientist II, Advanced Technology Group
4 weeks ago
Cambridge, Massachusetts, United States Editas Medicine Full timeJob Title: Scientist II, Advanced Technology GroupAt Editas Medicine, we're driven by a collective purpose to bring transformative and life-changing therapies to people living with serious diseases. This fuels our drive to excel in scientific innovation, harnessing the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.We believe our...