Research Associate III

3 days ago


Los Angeles, California, United States University of California Full time
Job Title: Staff Research Associate III

The University of California is seeking a highly skilled and dedicated Staff Research Associate III to join our esteemed research team.

In this role, the selected candidate will demonstrate outstanding expertise in in vivo techniques, focusing on the advancement of preclinical disease models within the field of oncology.

The models encompass a diverse array, including xenografts, orthotopic placements, and patient-derived xenografts (PDX). You will take on a central role in the initiation, supervision, and management of experimental rodent models.

This includes executing delicate survival surgeries and assuming comprehensive responsibility for all facets of animal studies, encompassing precise dose administration of therapeutic agents as well as radioactive compounds.

A critical aspect of this position involves conducting meticulous model characterization assays.

These assays encompass a spectrum of techniques, ranging from advanced histopathological analyses utilizing immunohistochemistry and immunofluorescence, to intricate autoradiography, flow cytometry, and ELISA procedures.

Furthermore, the incumbent will collaborate closely with the imaging center to proficiently execute preclinical imaging studies utilizing techniques such as PET, SPECT, CT, and Optical imaging.

In addition to the scientific responsibilities, the incumbent will play an integral role in maintaining the operational flow of the laboratory.

This includes managing the procurement and consumption of laboratory supplies, overseeing and coordinating the schedules of work-study students, and upkeeping and submitting updates for animal care protocols and radiation usage authorization.

Key Responsibilities:

  • Conduct in vivo experiments using rodent models
  • Develop and implement new research protocols
  • Collaborate with the imaging center to execute preclinical imaging studies
  • Manage laboratory supplies and equipment
  • Oversee and coordinate the schedules of work-study students

Requirements:

  • Basic understanding of biology, animal physiology, cancer biology, and/or molecular imaging research
  • Skilled with various preclinical models of disease
  • Ability to communicate effectively with a diverse group of faculty, staff, postdocs, and students
  • Experienced in working with small animals such as mice and rats
  • Ability to learn pre-clinical imaging systems

Preferred Qualifications:

  • Experience handling radioactive samples and knowledge of Radiation Safety requirements
  • Ability to learn ex vivo assays including autoradiography
  • Experience with in vitro binding assays, immunohistochemistry, and/or flow cytometry


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