Automation Specialist

1 month ago


South San Francisco, California, United States Vilya, Inc. Full time
Job Opportunity

Vilya, Inc. is a pioneering biotechnology company that leverages cutting-edge computational approaches to develop novel medicines. Our platform combines groundbreaking research with advanced computational methods to design new molecular structures that surpass those found in nature.

We are seeking an Automation Engineer to support our macrocycle discovery efforts. This individual will be responsible for operating, maintaining, integrating, and improving laboratory instrumentation and processes in collaboration with biology, structural biology, chemistry, compound management, DMPK, informatics, and molecular design teams.

Key Responsibilities:
  • Set up, operate, QC, and maintain instruments and HTS systems
  • Develop and execute HTS screening workflows for various drug targets, including automated HTS workflows, in collaboration with biology and chemistry teams
  • Develop and validate instrument integration and HTS data analysis workflows in collaboration with Informatics
  • Design, validate, implement, and continuously improve HTS-based processes and SOPs across established and novel technologies and instrumentation to support screening and drug discovery efforts
  • Work with compound management to support automation for compound delivery
  • Support instrumentation and automation needs across departments
  • Facilitate communication across departments, provide technical support, and training to colleagues with diverse backgrounds
Preferred Qualifications:
  • B.S. in mechanical, electrical, or chemical engineering, bioengineering, chemistry, biochemistry, or a relevant discipline with 5+ years of experience implementing and using laboratory automation/HTS systems
  • Hands-on experience in assay development, miniaturization, process development, and validation in automated HTS
  • Proficiency in programming languages such as Python, R, Java, or C# for scripting and integration with laboratory systems
  • Experience with instrument-specific software such as DART, SAMI EX is a plus
  • Experience with data integration and analysis workflows in collaboration with informatics and data science teams
  • Experience in mammalian cell culture and transfection
  • Hands-on experience with BioMek i7, PheraStar BMG microplate readers & microplate washers, ECHO 650 acoustic liquid handler, or similar systems, and LIMS/ELN
  • Proven experience in working in collaborative cross-functional teams
  • Strong problem-solving and critical-thinking skills
  • Creativity to develop tailored automation solutions to meet Vilya's needs
  • Excellent written and verbal communication skills, attention to detail, organizational skills, and the ability to collaborate effectively in a matrix environment are required
Vilya Benefits:
  • Opportunity to work in a disruptive startup with a talented, experienced team of dedicated individuals
  • 401(k) plan with employer matching for contributions
  • Stock options
  • Excellent medical, dental, and vision coverage
  • Open, flexible vacation policy
  • Support to attend professional conferences that are meaningful to your career growth
  • Monthly cell phone stipend
  • Commuter benefits
  • Salary Range: $125,000 - $164,000

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