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Senior Molecular Biologist

2 months ago

Princeton, New Jersey, United States Bristol-Myers Squibb Company Full time
Job Summary

Bristol-Myers Squibb Company is seeking a highly skilled Senior Molecular Biologist or Genomics Research Scientist to join our team. As a key member of our research team, you will be responsible for developing and implementing molecular assays and genomics data analysis to support clinical trial analysis.

Key Responsibilities
  • Develop and optimize molecular assays and genomics data analysis pipelines to support clinical trial analysis.
  • Collaborate with cross-functional teams to design and develop genomics and gene expression profiling (GEP) biomarker assays and technology platforms.
  • Develop and execute qualification/validation protocols for biomarker assays and technology platforms.
  • Provide subject matter expertise on genomics assay development, qualification/validation, and troubleshooting.
  • Work closely with data analysis teams and sample management teams to ensure accurate and reliable data analysis.
  • Develop and maintain a deep understanding of genomics and gene expression profiling (GEP) technologies and their applications in clinical programs.
  • Stay up-to-date with emerging technologies and advancements in genomics and gene expression profiling (GEP) and apply this knowledge to improve assay development and data analysis.
Requirements
  • Bachelor's Degree in a Life Science field or equivalent experience.
  • 8+ years of academic and/or industry experience in molecular biology, genomics, or a related field.
  • Master's Degree in a Life Science field or equivalent experience.
  • 6+ years of academic and/or industry experience in molecular biology, genomics, or a related field.
  • Ph.D. or equivalent advanced degree in a Life Science field.
  • 4+ years of academic and/or industry experience in molecular biology, genomics, or a related field.
Preferred Qualifications
  • Significant experience and subject matter expertise in PCR, NGS, or GEP application.
  • Experience with genomics platforms (NGS, qPCR, variant analysis platforms) for assay development, qualification/validation, troubleshooting, and reviewing run QC data.
  • Understanding of fit for purpose genomics assay validation principles for clinical assays.
  • Expertise in serving as subject matter expert on technology-specific data structure, data analysis, and data QC in working with data analysis teams and biostatistics teams.
  • Basic understanding of IP, contracting terms, and provisions.
  • Strong organizational, communication, interpersonal, and collaborative skills.
  • Excellent leadership and mentoring qualities for technical teams and matrixed teams.
  • Familiarity with genomics assay qualification/validation guidelines and guidance (FDA, CAP, CLIA, ACMG, NYSDOH, global regulatory requirements for assay development).
  • Basic understanding of IVD quality system standards (21 CFR part 820, ISO13485).
  • Knowledge of clinical sample analysis regulatory and quality frameworks and guidance in the lab and at vendors (such as GCP, CLIA, CAP, and NYDOH).