Director of High Throughput Process Automation

4 weeks ago


Columbus, Ohio, United States Sarepta Therapeutics Full time
About the Role

The Director of High Throughput Process Automation will lead the development and implementation of high throughput and process automation capabilities in the process and analytical development group at Sarepta Therapeutics.

This critical team leader will support the company's pipeline of cutting-edge recombinant AAV viral vector-based therapies by building and optimizing existing high throughput platforms and innovative process automation.

The ideal candidate will have extensive experience in high throughput and process automation, as well as excellent knowledge in programming and team management.

Key Responsibilities
  • Build and optimize high throughput platforms and innovative process automation in process and analytical development
  • Lead automation scientists and implement solutions for high throughput screens using various automation equipment
  • Evaluate, develop, and implement new technologies to Sarepta's Process and Analytical Development and Manufacturing platforms
  • Initiate investigation of new analytical approaches to a wide range of problems using scientific theory and technical literature
  • Work closely with team leaders in the ERPD organization and internal and external research teams to enable platform acceleration
  • Actively participate in various early research programs and cross-functional team meetings to play a key role as a subject matter expert for the process and technology
  • Provide guidance and direction to direct reports; establish goals, define roles, support career development, and manage performance
  • Ensure accurate and timely analysis of data to support preparation and submission of process and analytical method development reports
  • Support regulatory agency questions and prepare data for regulatory interaction as needed
Requirements
  • Advanced degree (MS or PhD) in Biochemistry, Bioengineering, Chemical Engineering, or a related field
  • 10+ years of relevant working experience within biotechnology/pharmaceutical industries
  • Extensive experience and excellent knowledge in high throughput and process automation and programming
  • Hands-on experience with the liquid automatic handler (Tecan or Hamilton)
  • Experience in managing teams of 5+ scientists/engineers
  • Experience in process and/or analytical development for viral vectors or other biologics
  • Experience with gene therapy with recombinant AAV vectors is a plus
  • Excellent written and verbal communication skills
  • Proven record of successfully planning experiments and executing projects in collaboration with internal or external stakeholders
  • Strong team player who works closely and effectively with cross-functional organizations
  • Proven ability to hire and integrate new talent into the organization, manage performance, develop people, and model the company's core values and culture


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