Senior Liver Research Expert

3 days ago


Étreux, Hauts-de-France, United States Takeda Pharmaceutical Full time

About the Role:

We are seeking a highly skilled Senior Liver Research Expert to join our team at Takeda Pharmaceutical. As a key member of our R&D organization, you will be responsible for validating novel targets and evaluating drug candidates for the treatment of chronic fibroinflammatory liver diseases.

In this role, you will apply your expertise in executing in vitro studies relevant to fibroinflammatory liver disease biology and pharmacology. You will play a central role in generating key data for evaluating potential targets, mechanism of action and/or drug candidate efficacy and pharmacodynamics.

With a strong background in cell culture and molecular biology, you will design and execute relevant target and drug candidate validation studies using contemporary methods and tools. You will also identify orthogonal applications of target, pathway, or platform biology in other fibroinflammatory diseases.

This is an exciting opportunity to work with a talented team of scientists and contribute to the development of innovative therapies for patients worldwide.

Responsibilities:

  • Execute in vitro studies on fibroinflammatory liver disease biology and pharmacology
  • Generate key data for evaluating potential targets and drug candidates
  • Design and execute target and drug candidate validation studies
  • Identify orthogonal applications of target, pathway, or platform biology

Requirements:

  • PhD degree in a scientific discipline (or equivalent)
  • Significant experience with drug discovery applications of cell culture
  • Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP
  • Experience working with live rodents and animal tissue


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