Lead Research Scientist for Liver Disease Innovation

3 days ago

Étreux, Hauts-de-France, United States Takeda Pharmaceutical Full time

About Takeda Pharmaceutical

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Takeda Pharmaceutical is a world-class R&D organization committed to unlocking innovation and delivering transformative therapies to patients worldwide. Our focus on three therapeutic areas and targeted investments enables us to bring life-changing treatments to those in need.

Job Summary

We are seeking a highly skilled Research Scientist, Liver Disease to join our team in Boston, MA. As a key member of our research group, you will contribute to the validation of novel targets and evaluation of drug candidates for the treatment of chronic fibroinflammatory liver diseases.

Your Key Responsibilities:

  • You will apply your expertise in executing in vitro studies relevant to fibroinflammatory liver disease biology and pharmacology.
  • Design and execute target and drug candidate validation studies using contemporary methods and tools.
  • You will play a central role in generating key data for evaluating potential targets, mechanism of action, and/or drug candidate efficacy and pharmacodynamics.
  • Implement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriate.
  • Identify orthogonal applications of target, pathway, or platform biology in other fibroinflammatory diseases.
  • Participate on cross-functional teams and provide technical leadership in your area of expertise.
  • Prepare technical reports, summaries, protocols, and quantitative analyses in written and/or oral form.
  • Maintain lab equipment and supplies as needed, ensuring a safe and organized lab environment.

Requirements/Qualifications

  • PhD degree in a scientific discipline or equivalent, with 6+ years of experience in vitro drug discovery research.
  • Demonstrated ability to independently solve scientific problems using multiple state-of-the-art technologies and approaches.
  • Significant experience with drug discovery applications of cell culture, including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models.
  • Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP.
  • Experience working with live rodents and animal tissue.
  • Exceptional project management skills and in-depth in vitro cell and molecular biology assay experience.

What We Offer

  • A competitive salary range of $108,500.00 per year, commensurate with experience.
  • U.S. based employees may be eligible for short-term and long-term incentives, medical, dental, vision insurance, a 401(k) plan, and company match.
  • New hires are eligible to accrue up to 120 hours of paid vacation and receive up to 80 hours of sick time per calendar year.
  • Takeda is an equal opportunity employer committed to creating a diverse workforce and providing equal employment opportunities to all employees and applicants without regard to race, color, religion, sex, sexual orientation, gender identity, or any other protected characteristic.

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