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Director of Functional Genomics and Research

2 months ago

South San Francisco, California, United States Amgen Full time
About the Role

We are seeking an experienced Executive Director to lead our Functional Genomics group at Amgen. As a key member of our Research Technologies department, you will be responsible for leading a research team focused on target discovery and biology, elucidating mechanism of action for therapeutics, phenotypic screening, biomarker discovery, and understanding resistance mechanisms.

Key Responsibilities
  • Supervise a group that will deliver critical, decision-making data regarding target discovery and biology to our pipeline through functional genomics, including CRISPR screening and advanced transcriptomics methods
  • Contribute to the development and implementation of the research strategy to integrate functional genomics and human genetics to understand target biology and de novo target discovery
  • Implement new gene editing technologies to stay at the cutting edge of functional genomics for target discovery and advancing our pipeline
  • Develop effective cross-functional relationships with colleagues in therapeutic areas, including Oncology, Inflammation, and Cardiometabolic, Small and Large Molecule Discovery, and our human genetics group at deCODE genetics
  • Become a leader within the Research Technologies department focused on progressing our small and large molecule pipeline from pre-discovery to IND through cutting-edge, innovative, technology-focused science
Requirements
  • Doctorate degree & 6 years of technology experience OR
  • Masters degree & 10 years of technology experience OR
  • Bachelors degree & 12 years of technology experience AND
  • 6 years of managerial experience directly managing people and leadership experience leading teams, projects, programs, and directing the allocation of resources
Preferred Qualifications
  • A proven track record of scientific innovation and accomplishment in functional genomics, as demonstrated by a strong publication record, patent submissions, and presentations at leading conferences
  • A deep understanding of CRISPR screening, gene editing technology, and transcriptomics approaches, including single cell sequencing and spatial transcriptomics
  • Demonstrated experience in phenotypic screening, both pooled and arrayed, using compounds and gene editing with whole genome and targeted libraries
  • Ability to advance functional genomics capabilities through technology development to stay at the cutting edge of this rapidly changing field
  • Strong written/verbal communication and interpersonal skills
  • Experience in leading, mentoring and developing the careers of a diverse and talented team
  • An ability to build strong and productive relationships with peers and cross-functional partners
What We Offer

As a valued member of our team, you will have access to a comprehensive benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. You will also be eligible for a discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan. Additionally, you will have the opportunity to participate in stock-based long-term incentives and enjoy award-winning time-off plans and bi-annual company-wide shutdowns.

About Amgen

At Amgen, our mission is to serve patients by pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. We are committed to creating a work environment that is inclusive, inspiring, and empowering, where our staff can thrive and make significant contributions for patients and our business. We are an Equal Opportunity employer and welcome applications from diverse candidates.