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Automation Specialist

1 month ago

Morrisville, North Carolina, United States Foundation Medicine, Inc. Full time
Job Summary

The Automation Specialist will be responsible for automating and scaling complex workflows and implementing processes for deployment in clinical laboratories at multiple sites. The ideal candidate will have experience working in a regulated environment and be familiar with robotic liquid handlers and other laboratory automation equipment. The Automation Specialist will identify problem areas and develop solutions to reduce Turn-Around-Time (TAT), increase sample processing capacity, and improve assay performance. The role will also involve performing installation and operational qualifications of automation equipment and generating documents required for this activity.

Key Responsibilities

  • Develop and improve robust automated solutions utilizing liquid handlers and other laboratory automation equipment designed to remove bottlenecks, increase capacity and reduce TAT in FMI's high throughput (24/7) Next Generation Sequencing lab.
  • Program, optimize, verify, and implement new and/or improved methods on robotic liquid handling workstations and integrated robotic systems.
  • Design and prototype components for integration of robotic systems through iterative improvements while working with scientists.
  • Provide on-site technical support of automation platforms.
  • Analyze workflows, identify bottlenecks, and develop solutions to improve efficiency, throughput, cost, and quality.
  • Generate and maintain requirements and test plan documentation.
  • Integrate instrument components and perform unit testing of instruments.
  • Contribute to innovation of current and new assays workflows, technologies, and processes.
  • Install, test and control new versions of automated protocols on applicable instrumentation across labs and possibly across sites.
  • Provide training and documentation for new or modified workflows to end users.

Qualifications:

  • One of the below education and experience combinations:
  • Bachelor's Degree in Bioengineering, Biotechnology or a similar life science AND 3+ years of related experience with high-throughput laboratory instrumentation; OR
  • Master's Degree in fields specified above and 2+ years of experience

Preferred Qualifications:

  • Experience working in a regulated environment (e.g. CLIA, CAP, ISO, GxP)
  • Previous experience working in a molecular diagnostics/clinical laboratory setting
  • Familiarity with VBscript, Python, PERL and/or JavaScript, relational databases, SQL, and LIMS or other relevant enterprise software packages
  • Ability to work in a lab environment in the presence of chemicals and reagents.
  • Experience with robotic liquid handlers from Hamilton, TECAN, Agilent Technologies, Dynamic Devices or Beckman Coulter
  • Developing and implementing integrated robotic systems for use in a high throughput environment
  • Developing, optimizing, and validating assays for use in a high throughput environment
  • Standard molecular biology techniques such as nucleic acid isolation, purification and quantitation, bioanalyzer, DNA/RNA quantitation, qPCR or Next Generation Sequencing
  • Familiarity with streamlining workflows and developing automated laboratory processes and instrumentation systems, including collecting and documenting requirements, developing concepts, design, testing/validation, implementing, and training
  • Experience communicating and collaborating with internal and external colleagues and customers from diverse scientific, engineering, operational, and regulatory disciplines
  • Ability to work as an individual as well as in a team environment
  • Knowledge of safety protocols in a laboratory setting
  • Strong written and oral communication skills
  • Detail oriented and well organized
  • Understanding of HIPAA and the importance of patient data privacy

Commitment to reflect FMI's values:
patients, passion, innovation, and collaboration. #LI-Onsite