Senior Research Scientist, Protein Analytics and Biophysics

3 days ago


Somerville, Massachusetts, United States Generate:Biomedicines Full time
About Generate:Biomedicines

Generate:Biomedicines is a pioneering therapeutics company that leverages the intersection of machine learning, biological engineering, and medicine to create breakthrough medicines. Our platform uses Generative Biology to computationally generate novel therapeutics, revolutionizing the field of biotherapeutic development.

The Role

We are seeking a highly experienced and motivated Principal Scientist to join our multidisciplinary Protein Analytics & Biophysics team. The successful candidate will lead efforts in evaluating protein-protein binding interactions using a range of biochemical and biophysical technologies. This will involve designing and executing fit-for-purpose binding assays and workflows, analyzing and interpreting complex data sets, and collaborating with computational scientists and project teams to support critical decision-making checkpoints.

Key Responsibilities
  • Drive the design and execution of binding assays and workflows using techniques such as surface plasmon resonance (SPR), bio-layer interferometry (BLI), and kinetic exclusion assay (KinExA)
  • Analyze and interpret complex data sets using a range of digital tools
  • Pioneer efforts to maximize productivity and streamline processes by integrating new and innovative technologies
  • Collaborate with computational scientists and project teams to support critical decision-making checkpoints
  • Provide technical oversight and strategic guidance to functional team members
Requirements
  • PhD in a scientific field of study and 8+ years of relevant research experience, or Master's degree in a scientific field of study and 14 years of relevant research experience, or B.S. in a science-related discipline with 16+ years of relevant research experience
  • Deep expertise and extensive hands-on experience in biomolecular interaction analysis using biosensor-based platforms and solution-based approaches
  • Highly skilled in experimental design and data analysis
  • Proficient in integrating experimental data into Laboratory Information Management Systems (LIMS)
  • Knowledge of traditional protein characterization and developability techniques
  • Experience in preparing nonclinical documentation for intellectual property applications and regulatory filings
What We Offer

Generate:Biomedicines offers a dynamic and collaborative work environment, with opportunities for professional growth and development. We are committed to fostering a culture of innovation and excellence, and we are seeking talented individuals who share our passion for impact.



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