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Lead Protein Scientist
2 months ago
Ordaōs is a pioneering company at the intersection of human expertise and machine-driven drug design. Our innovative solution, mini-PROTM, represents a unique class of mini-proteins that assist pharmaceutical and biotechnology firms globally in delivering safer and more effective life-saving treatments in significantly less time than traditional discovery methods.
miniPRO proteins are meticulously crafted and assessed using in silico methods, followed by rigorous in vitro and in vivo testing. At Ordaōs, we are transforming the landscape of drug discovery into a more efficient drug design process.
The Opportunity
Our Protein Assay Development team is looking for a Lead Protein Scientist to play a crucial role in our biologics drug development initiatives. We seek individuals who are critical thinkers with a strong desire to learn and adapt to new methodologies. This role requires flexibility and the capacity to excel in a dynamic environment.
This Lead Scientist will engage in various projects and experiments within our laboratory, focusing primarily on high-throughput screening, quality control, lab automation, and the optimization of protocols and methods.
Key Responsibilities:
Method Development:
- Design, develop, and execute experimental protocols aimed at enhancing protein expression, purification, and analytical methods.
- Analyze experimental data and interpret results to refine procedures.
- Collaborate with cross-functional teams to integrate optimized methods into standard workflows.
Protein Quality Assurance:
- Conduct high-throughput screening and quality control assessments of proteins utilizing diverse biochemical and biophysical techniques.
- Develop and validate assays for protein characterization, ensuring high reproducibility and accuracy standards.
- Maintain meticulous records of experimental data, ensuring comprehensive documentation of procedures, observations, and results.
- Communicate findings effectively to the team, providing clear reports that support informed decision-making.
Laboratory Automation:
- Operate and maintain advanced automated laboratory equipment for high-throughput protein production and analysis, ensuring optimal performance and data integrity.
- Manage cutting-edge instruments and complex workflows, troubleshooting technical issues as they arise.
- Develop and implement automation protocols to enhance laboratory efficiency and throughput.
- Troubleshoot and refine automated workflows to ensure consistent and reliable performance.
Qualifications:
- Bachelor’s or Master’s degree in biology or a related discipline.
- 5-6 years of experience in high-throughput screening and automation.
- Familiarity with laboratory automation tools and software.
- Experience in a fast-paced startup environment.
- Proficiency in Python programming.
- Knowledge of protein purification techniques.
- Strong analytical and problem-solving capabilities.
- Excellent communication and teamwork skills.
- Experience in designing and implementing robotic systems for laboratory automation.
Preferred:
- Experience with Benchling software.
- Familiarity with cell-free expression systems.
Benefits:
- Potential for ISO grants based on performance.
- Competitive healthcare coverage, including dental and vision plans.
- Health savings account program with maximum employer contributions.
- 401k plan with a 100% match on the first 4% of contributions.
- Generous paid vacation and sick leave policies, along with company-paid holidays.
- Annual corporate membership to Citibike.
- Monthly commuter benefits.
- Four weeks of paid compassionate leave for unforeseen events.
Ordaōs is dedicated to fostering an inclusive workplace and provides equal employment opportunities without discrimination based on race, color, gender, age, religion, national origin, disability, veteran status, genetic information, sexual orientation, or any other characteristic protected by law. We are committed to making reasonable accommodations for qualified individuals with known disabilities.
