Scientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)
4 months ago
Scientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)
- Full-time position
- Competitive compensation (Salary, Benefits & Options)
- 180 Varick Street, New York, and 430 E 29th Street, New York
Waypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast but inaccurate, and in vivo approaches that are accurate but slow and expensive. Using our proprietary platform combining spatial biology, pooled screening, in silico protein engineering, and machine learning, we can obtain both depth and breadth when screening cell therapy candidates – speed without compromising on in vivo accuracy. Our team is highly collaborative, interdisciplinary, and shares the mission of developing novel immune cell therapies to benefit patients' lives.
Position Summary:
We are seeking a highly motivated, creative scientist who thrives in a fast-paced and collaborative environment. The ideal candidate will have extensive expertise in immunology, including a deep understanding of either regulatory T cells (Tregs) or the design of engineered T cell therapies (e.g. CAR-Treg, CAR-T, TCR-T, or others). Their primary tasks will be to apply their knowledge of the immune system to design novel T cell therapies, optimize the manufacturing of these cell therapies using multiplexed cloning and T isolation & genetic engineering approaches, and then test their function using in vitro and in vivo models of diseases. In this role, you will work collaboratively with our team of computational and wet-lab scientists to develop cutting-edge technologies and new therapeutic options for patients.
Duties and Responsibilities
- Apply your knowledge of immune-related signaling pathways & protein domains to improve the efficacy of existing T cell therapies.
- Generate hundreds of innovative designs for cell therapies that address the challenges in different disease indications, with a focus autoimmune diseases and solid tumors.
- Work independently to optimize the manufacturing conditions for Treg and CAR T cell therapies, and implement these strategies to generate libraries of T cell therapies.
- Develop in vitro assays and in vivo models of Treg function, and work collaboratively to implement these assays to compare the function of different Treg cell therapy designs.
- Implement existing strategies for highly multiplexed cloning, using either pooled cloning or arrayed cloning approaches.
- Introduce new technologies and improve the performance, throughput, and accuracy of existing assays
- Actively engage in prioritizing key milestones and developing appropriate timelines
- Provide conceptual input on experimental design and interpretation in a team setting
Required Qualifications
- Ph.D. in Immunology, Cancer Biology, Protein Design, Cell Biology, or a related field. Alternatively, M.S. or B.S. degree with 5 years or 7 years of equivalent experience, respectively.
- 4+ years of academic or industry experience working on immunology and T cell biology.
- Experience culturing T cells ex vivo and using these cells for downstream assays.
- Strong molecular biology skills for cloning (e.g. Gibson Assembly) and genetic engineering of mammalian cells (e.g. viral approaches, CRISPR systems).
- Knowledge of the interplay between the immune system and either healthy tissues or the tumor microenvironment.
- Practical knowledge of the immune cell therapy field.
- An excellent scientific track record with published papers or recent experience in immunology or cell therapy.
- Superb written and oral communication skills, and the organizational abilities to pursue several projects on tight timelines.
Preferred Qualifications
- Deep expertise in the design and testing of engineered Treg cell therapies (e.g. CAR-Treg, armored T cell therapies) for autoimmune and inflammatory indications.
- Knowledge of the mechanisms used by Treg cells to dampen immune responses in a variety of tissue contexts.
- Experience designing novel in vitro assays or animal models for autoimmune and inflammatory indications.
Send CV and cover letter to apply:
jobs@waypointbio.com
-
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)Full-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell...
-
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)Full-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell...
-
Scientist / Senior Scientist, In Vivo Cancer Biology
2 months ago
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, In Vivo Cancer BiologyFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Scientist / Senior Scientist, In Vivo Cancer Biology
2 months ago
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, In Vivo Cancer BiologyFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Scientist / Senior Scientist, In Vivo Cancer Biology
2 months ago
New York, United States Waypoint Bio Full timeScientist / Senior Scientist, In Vivo Cancer BiologyFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Associate Scientist
3 months ago
New York, United States Waypoint Bio Full timeAssociate Scientist / Senior Associate ScientistFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, NY, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Associate Scientist
3 months ago
new york city, United States Waypoint Bio Full timeAssociate Scientist / Senior Associate ScientistFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, NY, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Associate Scientist
3 months ago
new york city, United States Waypoint Bio Full timeAssociate Scientist / Senior Associate ScientistFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, NY, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Contract Scientist, In Vivo Cancer Biology
6 months ago
New York, United States Waypoint Bio Full timeContract Scientist, In Vivo Cancer BiologyPart-time positionCompetitive compensation430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors, including CAR-T, CAR-NK, and TCR-T. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast...
-
Contract Scientist, In Vivo Cancer Biology
2 months ago
new york city, United States Waypoint Bio Full timeContract Scientist, In Vivo Cancer BiologyPart-time positionCompetitive compensation430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors, including CAR-T, CAR-NK, and TCR-T. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast...
-
Contract Scientist, In Vivo Cancer Biology
1 month ago
new york city, United States Waypoint Bio Full timeContract Scientist, In Vivo Cancer BiologyPart-time positionCompetitive compensation430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors, including CAR-T, CAR-NK, and TCR-T. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast...
-
Biomaterials Scientist
3 weeks ago
New York, New York, United States Gameto Full timeTransforming the Future of Women's HealthGameto is a pioneering biotechnology company committed to advancing treatments for menopause, infertility, and other diseases affecting the female reproductive system.We're seeking an experienced Scientist to lead cutting-edge research at the intersection of cell biology, biotechnology, and women's health,...
-
Research Scientist
3 weeks ago
New York, New York, United States Waypoint Bio Full timeJob SummaryWe are seeking a highly organized and enthusiastic research professional to join our team at Waypoint Bio. As a Research Scientist, you will have the opportunity to develop scientific knowledge and skills while providing technical support. You will work collaboratively on multiple projects, including cell culture, lentivirus production, and...
-
Cell Scientist Researcher
3 weeks ago
New York, New York, United States Gameto Full timeAbout the RoleThis is a unique opportunity to join our innovative team at Gameto as a Scientist (I-III) in Cell Science to contribute to the development of novel cell therapies for menopause.As a key member of our team, you will play a pivotal role in leading and executing research projects focused on developing innovative cell therapies for menopause using...
-
ENVIRONMENTAL SCIENTIST
4 weeks ago
New Albany, United States EMH&T Full timeJob DescriptionJob DescriptionEMH&T is currently seeking an Environmental Scientist to join Environmental team located in Columbus, OH. The Environmental Scientist will work under the mentorship of a Senior Environmental Scientist and will contribute to our environmental projects and play a pivotal role in our continued success. You will support our team of...
-
Associate Scientist
2 weeks ago
New Haven, United States Piper Companies Full timePiper Companies is actively seeking a Associate Scientist to join a join a dynamic and fast-paced team focused on developing therapies to degrade disease-causing proteins for diseases related towards CNS. This position is located in New Haven, Connecticut. The Associate Scientist is a laboratory/wet bench based role that will conduct biochemistry techniques...
-
Computational Scientist in Single Cell Genomics
4 weeks ago
New York, New York, United States New York Genome Center Full timeJob DescriptionThe New York Genome Center is seeking a highly skilled Computational Scientist to join our team in the Technology Innovation Lab. As a key member of our team, you will be responsible for developing and implementing cutting-edge computational methodologies and technologies to advance our understanding of disease mechanisms.Key...
-
Associate Research Scientist
4 weeks ago
New York, New York, United States New York Genome Center Full timeAbout the Satija LabThe Satija lab is a dynamic research environment that focuses on single cell genomics. We are seeking an enthusiastic and highly motivated Associate Research Scientist to assist in the development of new technologies for single cell sequencing.Key ResponsibilitiesMaintain lab stocks and order supplies, perform lab management and...
-
Senior Data Scientist
4 weeks ago
New York, New York, United States Digital Turbine Full timeWe are seeking a highly skilled Senior Data Scientist to join our team at Digital Turbine. As a Senior Data Scientist, you will be responsible for building and deploying Machine Learning models to production on a massive scale, serving 2 billion devices globally and handling 200 billion requests every day.Our team is passionate about using data to drive...
-
Senior Data Scientist
4 weeks ago
New York, New York, United States Luminary Group LLC Full timeLuminary Group LLC is seeking a highly skilled Senior Data Scientist to join their team. As a Senior Data Scientist, you will be responsible for driving the analysis and interpretation of real-world data to generate valuable insights and support evidence-based decision making in the healthcare industry.Lead and guide the development and implementation of...
