Scientist 1, Chemistry Development
2 weeks ago
**Job Title: Scientist 1, Chemistry Development**
**Location: 7 Loveton Circle, Sparks, MD 21152**
**Duration: 12 months contract (Temp to Perm possibility)**
**Shift: M - F 8:30am -- 5pm**
**Client: Becton and Dickinson (BD)**
Must Haves:
Working with Hazardous chemicals
Wet Chemistry
Develop, follow protocols and perform analytical testing using wet chemistry analysis, UV/VIS Spectroscopy, UPLC/MS, FTIR, ICP-MS and other techniques as required.
HPLC
**Description**:
Works within a team to provide synthetic oligonucleotides through the use of automated oligonucleotide synthesizers and Liquid Chromatography systems which support the development of automated assays using nucleic acid isolation and real-time amplification/detection technology within the Molecular Diagnostic plants.
**DUTIES AND RESPONSIBILITIES**:
1. Follows established protocols for the synthesis and purification of oligonucleotides used in manufacturing and R&D.
2. Follows established protocols for the preparation of buffers used in the oligonucleotide and conjugation processes.
3. Follows established protocols for protein conjugation procedures.
4. Contributes to the completion of goals associated with specific oligonucleotide process optimization projects.
5. Contributes to developing solutions and providing recommendations as to the appropriate course of action to technical problems associated with the preparation of synthetic oligonucleotides.
6. Provides documentation and validation support in execution of synthesis and/or purification process changes.
7. Performs laboratory work and documentation in accordance with GMP, GLP and company guidelines.
8. Perform tasks under general supervision.
**Qualifications**:
**KNOWLEGDE AND SKILLS**:
- Basic understanding in the use of the liquid chromatography manual or automated systems.
- Basic understanding of chromatography theory and hands-on experience with HPLC
(High Performance Liquid Chromatography).
- Excellent verbal and written communication skills are necessary together with the
ability to interact effectively in team and cross-functional environments.
- Understanding of the GMP and GLP laboratory guidelines.
- Optional experience includes the use of a DNA (oligonucleotide) and/or Peptide
synthesizer and having an understanding of the oligonucleotide synthesis chemistry.
- Understanding of Lean manufacturing tools highly beneficial.
**EDUCATION AND EXPERIENCE**
- Minimum of a Bachelor’s Degree in Biochemistry, Chemistry, Molecular Biology or
related discipline.
- Prefer a minimum of 1 year of industrial or academic experience in the synthesis and/or purification of oligonucleotides.
**Job Type**: Contract
Pay: $30.00 - $34.00 per hour
Schedule:
- 8 hour shift
- Day shift
Ability to Relocate:
- Sparks Glencoe, MD 21152: Relocate before starting work (required)
Work Location: In person
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