Scientist
4 weeks ago
Pay Range $30.50hr - $34.50hr
Responsibilities:
- Follows established protocols for the synthesis and purification of oligonucleotides used in manufacturing and R&D.
- Follows established protocols for the preparation of buffers used in the oligonucleotide and conjugation processes.
- Follows established protocols for protein conjugation procedures.
- Contribute to the completion of goals associated with specific oligonucleotide process optimization projects.
- Contributes to developing solutions and providing recommendations as to the appropriate course of action to technical problems associated with the preparation of synthetic oligonucleotides.
- Provides documentation and validation support in the execution of synthesis and/or purification process changes.
- Performs laboratory work and documentation in accordance with GMP, GLP and company guidelines.
- Perform tasks under general supervision.
Knowledge And Skills:
- Basic understanding in the use of the liquid chromatography manual or automated systems.
- Basic understanding of chromatography theory and hands-on experience with HPLC
- (High-Performance Liquid Chromatography).
- Excellent verbal and written communication skills are necessary together with the ability to interact effectively in team and cross-functional environments.
- Understanding of the GMP and GLP laboratory guidelines.
- Optional experience includes the use of a DNA (oligonucleotide) and/or Peptide synthesizer and having an understanding of the oligonucleotide synthesis chemistry.
- Understanding Lean manufacturing tools is highly beneficial.
- Minimum of a Bachelor s Degree in Biochemistry, Chemistry, Molecular Biology or related discipline.
- Prefer a minimum of 1 year of industrial or academic experience in the synthesis and/or purification of oligonucleotides.
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