Research Fellow

3 weeks ago


Boston, United States Mass General Physicians Organization(MGPO) Full time

**Research Fellow**
- (3291380)

The laboratory of Dr. Michael Honigberg at the Massachusetts General Hospital Cardiovascular Research Center (CVRC) and Broad Institute of MIT & Harvard has a unique post-doctoral fellow position open for a highly qualified applicant interested in investigation at the intersection of cardiovascular, reproductive, and aging biology. The new hire will be appointed as a Research Fellow at the Massachusetts General Hospital and Post-Doc at the Harvard Medical School.
- The Honigberg lab aims to advance mechanistic understanding of emerging cardiovascular risk factors and inform new paradigms for health promotion and disease prevention. Current projects focus on pregnancy (e.g., preeclampsia/eclampsia), menopause, aging biology, community-based research and health disparities, and novel lipid-modifying therapies, among other topics.

Overall, this is a unique opportunity to engage in cutting edge science and make a central contribution to biomedical research. In addition, MGH and the Broad Institute provide vibrant research environments with close links to top academic and industry networks across the Greater Boston area and the world.
- Key Responsibilities
- Construction and implementation of cloud-based pipelines for genomic, polygenic risk scoring, and biostatistical analyses.
- Processing and quality control of next-generation sequencing data.
- Processing and quality control of multi-omics data.
- Statistical analyses of genotype-phenotype association analyses, with summarization and graphical representations.
- Organizing, manipulating, and harmonizing new datasets across different formats and synchronization with existing datasets and databases.
- Phenotypic curation from electronic health record structured and unstructured data.
- Construction, implementation, and sensitivity analyses of biostatistical models in classical epidemiology, genetic epidemiology, and machine learning.
- Lead and contribute to manuscript preparation as well as internal and external project-team reports.
- Actively participate and present in project meetings and lab meetings.
- Doctoral degree in computational biology, biomedical informatics, biostatistics, statistical genetics, genetic epidemiology, or computer science.
- First (or co-first) author of one or more peer-reviewed scientific publications.
- Excellent English verbal and written communication skills.
- Able to work both independently and in a team.
- Strong record of productivity, motivation, adaptability, and collaboration.
- Exceptional oral and written communication skills.
- Strong background in computational biology and bioinformatics.
- Strong skills in statistical analyses are highly preferred.
- Strong demonstrable proficiency in UNIX, R, Python, and Perl; facility with Java, Matlab, C, C++ preferred.
- Strong facility with cloud computing.
- Prior experience in human genetic analyses and bioinformatics analyses of publicly available datasets.
- Familiarity with next-generation sequence data analysis tools strongly preferred.
- Ability to adapt to rapidly changing and high-demand environments.
- Knowledge of cardiovascular disease is not required.

**EEO Statement**

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.

**Primary Location** MA-Boston-MGH 185 Cambridge

**Work Locations** MGH 185 Cambridge 185 Cambridge Street Boston 02144

**Job** MD/PHD/Fellows/ PostDocs

**Organization** Mass General Physicians Organization(MGPO)

**Schedule** Full-time

**Standard Hours** 40

**Shift** Day Job

**Posted Shift Description** MGH Cardiovascular Research Center's Honigberg Lab is recruiting a Research Fellow with an interest in investigation at the intersection of cardiovascular, reproductive, and aging biology

**Employee Status** Regular

**Recruiting Department** MGH Cardiovascular Research Center

**Job Posting** May 24, 2024


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