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Associate, Scientist I/ii
3 months ago
**Company Description**
Associate Scientist I/II, CMC Biologics Drug Product Development
The Biologics Drug Product Development group develops antibody drug conjugates (ADC) and other biologics by state-of-the-art formulation and analytical technologies. We create valuable intellectual property through new formulation compositions and prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content.
**Key Responsibilities Include**:
- Support Formulation development activities to enable first-in-human clinical studies.
- Execute studies evaluating the stability (chemical & physical) of biologics against solution conditions (pH, ionic strength, temperature, light, etc.) and physical stresses arising from manufacturing process conditions (freeze thaw, mixing, filtration, filling, and lyophilization), and screen excipients (buffers, stabilizers, surfactants, etc.) to develop robust formulations for frozen, refrigerated liquid, and lyophilized dosage forms.
- Perform lab-based studies including study design, preparation, execution, data collection, analysis, presentation, and report writing.
- Prepare concise and sound scientific presentations of experimental results to management and assist in authoring detailed scientific technical reports.
**Qualifications**
- **
Associate Scientist I: BS in a scientific field**:
- **Associate Scientist II: BS or MS in a scientific field and typically 3 (BS) or 0 (MS) years of relevant experience**:
- Hands-on experience using analytical methods for chemical and structural characterization of proteins e.g. chromatography, capillary electrophoresis, particle analysis, and other biophysical techniques (UV-vis, DLS, DSC, etc.) for protein characterization.
- Scientific problem solving, experimental design, and trouble shooting skills.
- Scientific understanding of the structure & function of monoclonal antibodies, antibody constructs/conjugates, bispecifics, and fusion proteins and their modes of degradation/stabilization.
**Key Leadership Competencies**:
- Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.
- Excellent oral communication skills in a scientific setting, as well as sound technical writing and documentation competencies are required.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
**Additional Information**
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is a considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
