Research Technician

3 weeks ago

Boston, United States Dana-Farber Cancer Institute Full time

**Job ID**:
39542

**Location**:
450 Brookline Ave, Boston, MA 02215

**Category**:
Research Laboratory

**Employment Type**:
Full time

**Work Location**:
**Onsite**: 100% onsite

Overview

The Center for Early Detection and Interception of Blood Cancers

is the first-of-its-kind clinic for patients with precursor conditions of hematologic malignancies. As part of the Hematologic Oncology Treatment Center, the Center builds on Dana-Farber's past and ongoing research efforts for precursor conditions. The clinic evaluates individuals diagnosed with these conditions or at high risk for disease development and works with patients to manage their risk of disease progression.

Our research team is committed to early detection and intervention to prevent precursor conditions from progressing to incurable blood cancers. Our center offers patients a range of clinical trials, including screening, treatment, and non-therapeutic trials that will help us to better understand and care for patients with precursor hematologic conditions.

Within this context, our scientific teams play an important role in driving discovery, innovation, and translation. Our research technicians support this research in everything from the selection and processing of our patient samples to the most advanced laboratory assays.

The Research Technician will perform scientific research, development and/or clinical tasks of varying complexity. They will perform set up, operation and maintenance of laboratory instruments and equipment, performing and monitoring of experiments, making observations and calculating and recording results to meet the requirements of industry sponsored and or grant funded research agreements. They must maintain a professional demeanor in communications with collaborators. They must be able to take necessary initiative and accountability to meet project timelines and deliverables.

**Responsibilities**:
**GENERAL DUTIES AND RESPONSIBILITIES**:
Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
Clean, maintain and prepare supplies and work areas and responsible for ordering of supplies. Collaborates with Purchasing and responsible for negotiating with vendors.
Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.
Isolate, identify and prepare specimens for examination.
Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. Will be expected to participate in formal and information presentations ofresults to staff and collaboration partners.
Maintains detailed notebook of all work-related activities and support patent invention disclosures and IND enabling filing.
Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
Responsible for the development, modification and improvement of standard operating procedures and provide detailed protocols as specified by sponsored research agreements.
Responsible for designing and executing advanced experiments and setting strategy.
Responsible for troubleshooting and Quality Control of experiments.
Responsible for communications and managing interactions with collaborators.
Responsible for meeting project deliverables and timelines.
May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
May be responsible for monitoring laboratory budgets.
Performs other responsibilities as required.

TYPICAL RESEARCH WORK WILL VARY BY PROJECT, BUT MAY INCLUDE, AMONG OTHERS:
In vivo and in vitro work, Tissue Culture, Lentiviral work, Cell sorting and staining, Western blots, PCR and Gel Electrophoresis, qPCR/RT-qPCR assays, cell enumeration imaging & analysis, Bradford/Pierce BCA protein assays, Cloning and Plasmid preparation, DNA and RNA sequencing library preparation, Lineage tracing, Flow cytometry, AUTOMacs selection, MALDI-TOF mass spectrometry, imaging mass spectrometry, maintain laboratory inventory databases, operate liquid handler

**SUPERVISORY RESPONSIBILITIES**:
No supervisory responsibilities.
Normally receives detailed instructions on all work. Works within a highly collaborative matrixed team environment while maintaining independent responsibilities.
Contributes to the planning and coordination of group efforts.

**PATIENT CONTACT**:
None.

**WORKING CONDITIONS**:
Performs operations in a lab environment, works with or around potentially hazardous materials. Requires initial Lab Safety training and annual safety retraining.

**Qualifications**:
**MINIMUM JOB QUALIFICAT

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