Molecular Genomic Specialist I

1 month ago

Pittsburgh PA United States UPMC - Pittsburgh Medical Center Full time
Job Description

UPMC Presbyterian is hiring a Molecular Genomic Specialist I to support the Molecular and Genomic Pathology Laboratory (MGP)  This is a daylight position working Monday through Friday - no weekends or holidays are required

The Molecular and Genomic Pathology Laboratory (MGP) is a dynamic state-of-the-art clinical laboratory that prides itself on providing the highest quality of patient care in the fields of inherited diseases, hematological malignancies, and solid tumors utilizing cutting-edge molecular testing platforms and informatics approaches exemplified by next-generation sequencing. MGP offers its staff a challenging and rewarding career by offering a wide variety of job responsibilities as well as opportunities to identify and build upon individual strengths. MGP promotes lab-wide collaboration and teamwork where each staff member is valued for the unique skill set they can offer the team

We are currently offering a generous sign-on bonus for this role

  • Sign-On Bonus Details: $15,000 for a 3-year commitment


Responsibilities:
  • Accurately record relevant data and values in case folders and internal databases.
  • Adhere to established laboratory and hospital policies and good clinical laboratory practice in areas of procedures, quality control, quality assurance, and safety and compliance.
  • Appropriately use automated and/or liquid handling machines for clinical testing.
  • Accurately and precisely analyze molecular assay results for final interpretation by medical staff.
  • Effectively communicate with other laboratory members including lab leadership. Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities.
  • Identify critical, abnormal, and/or unacceptable results and follow-up according to established protocol.
  • Document all corrective actions and follow up with the lead and/or supervisor.
  • Independently perform clinical testing per established SOPs. Process all clinical, QC, and PT specimens through clinical workflow.
  • Demonstrate high-level problem-solving skills and analytical abilities to successfully perform laboratory testing.
  • Maintain expertise in or knowledge of molecular biology techniques, including but not limited to: nucleic acid isolation, nucleic acid quantitation, PCR/RT-PCR/qPCR, Sanger sequencing, LOH, methylation analysis, MassARRAY MALDI-TOF, next-generation sequencing, etc.
  • Maintain proficiency in appropriate Laboratory Information Management Systems (LIMS).
  • Operate, perform routine maintenance on, and calibrate all laboratory equipment as required.
  • Identify problems with instrumentation, methodology, specimens, and/or supplies and follow-up according to established protocols.
  • Process samples meticulously to avoid cross-contamination.
  • Meet established turn-around-time deadlines for clinical testing.

Molecular procedures are highly complex assays that have multiple steps over a series of several days.  There are Quality Control check-points at each step, but the end result of every assay requires every technologist to evaluate assay performance as a whole as well as individual sample performance. Specific to molecular laboratories, technologists must: 

  • Be able to pipet accurately and precisely.

  • Have scientific knowledge of molecular fundamentals and techniques, in order to understand the methodology of the assay and execute it properly both manually and using advanced instrumentation.

  • Possess high-level problem-solving skills for assay, instruments, controls, samples, and reagents/enzymes so they are able to notice, understand, and act upon performance trends of every step of every assay.

  • Understand basic molecular workflow principles and required proper precautions to ensure assay and specimen integrity.                                                                                                      

Molecular Genomic Specialist I:

  • BS degree, major in a biological science field; OR

  • BS degree in chemical or physical science field with at least 1-year experience in clinical molecular laboratory AND 16 semester hours in chemistry (including at least 6 hours in inorganic chemistry), 16 semester hours in biology courses pertinent to the medical sciences, and 3 semester hours in mathematics.

  • 1 year of clinical molecular laboratory experience OR 1 year of experience through training in appropriate molecular laboratory coursework

  • Prior clinical lab experience and specifically NGS testing experience preferred.

Licensure, Certifications, and Clearances:

  • (MB) ASCP certification preferred.
  • Act 34

UPMC is an Equal Opportunity Employer/Disability/Veteran

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