Current jobs related to Senior Scientist/Principal Scientist - San Diego - Society of Exploration Geophysicists
-
Senior Principal Scientist
2 weeks ago
San Diego, California, United States Pfizer Full timePfizer's Oncology Research Unit (ORU) in La Jolla, California, is seeking a Senior Principal Scientist (PhD) to join the Tumor Immunity team focused on delivering breakthroughs that change patients' lives by redirecting the immune system against cancer.The Senior Principal Scientist will be responsible for driving scientific strategies and their...
-
San Francisco, California, United States Genentech Full timeJob OpportunityWe are seeking a highly motivated and experienced Senior/Principal Scientist to lead lab-based translational research and discovery efforts in the clinical proteomics and mass spectrometry laboratory.Key ResponsibilitiesDesign and execute mass spectrometry/clinical proteomics experiments to explore novel biomarker hypotheses and collaborate...
-
Principal Scientist Pharmacometrics Lead
2 weeks ago
San Diego, California, United States Affinity Executive Search Full timeJob Title: Principal Scientist PharmacometricsA top-tier BioPharmaceutical company is seeking a highly skilled Principal Scientist to join their dynamic Pharmacometrics team.The Pharmacometrics Group applies a range of model-informed drug development (MIDD) approaches to support early and late-stage development of small and large molecules.We are looking for...
-
Principal Scientist, Analytical Development
3 weeks ago
san diego, United States Meet Full timePrincipal Scientist, Analytical DevelopmentRole will be 4-5x days per week onsite in San Diego, CAMeet has partnered with a clinical stage biotech based in San Diego that is looking for a Principal Scientist, Analytical Development to join their team! Our client is focused in a few main therapeutic areas (anti-infective, autoimmune, immunology) and has...
-
Principal Scientist, Analytical Development
2 months ago
San Diego, United States Meet Full timePrincipal Scientist, Analytical DevelopmentRole will be 4-5x days per week onsite in San Diego, CAMeet has partnered with a clinical stage biotech based in San Diego that is looking for a Principal Scientist, Analytical Development to join their team! Our client is focused in a few main therapeutic areas (anti-infective, autoimmune, immunology) and has...
-
Principal Scientist, Analytical Development
3 weeks ago
San Diego, United States Meet Full timePrincipal Scientist, Analytical DevelopmentRole will be 4-5x days per week onsite in San Diego, CAMeet has partnered with a clinical stage biotech based in San Diego that is looking for a Principal Scientist, Analytical Development to join their team! Our client is focused in a few main therapeutic areas (anti-infective, autoimmune, immunology) and has...
-
Principal Data Scientist
3 weeks ago
San Francisco, California, United States DaVita Full timeJob Title: Principal Data ScientistAt SoFi, we're shaping a brighter financial future with our members. We're a next-generation financial services company and national bank using innovative, mobile-first technology to help our millions of members reach their goals.We're seeking a Principal Data Scientist with strong engineering skills to lead the domain of...
-
Medicinal Chemistry
3 days ago
San Diego, United States Society of Exploration Geophysicists Full timeLight Horse Therapeutics is a small molecule drug discovery company based in San Diego, employing tools from chemical and computational biology, in conjunction with precision genome editing methods to identify functional/ligandable sites on high value oncology protein targets for therapeutic intervention. Light Horse therapeutics was founded by leading...
-
Principal Scientist
13 hours ago
San Diego, United States Trc Companies, Inc. Full timeAbout UsGroundbreaker. Game changer. Pioneer.TRC has long set the bar for clients who require more than just engineering, combining science with the latest technology to devise innovative solutions that stand the test of time. From pipelines to power plants, roadways to reservoirs, schoolyards to security solutions, clients look to TRC for breakthrough...
-
Principal Scientist
13 hours ago
San Diego, United States TRC Companies, Inc. Full timeAbout Us: Groundbreaker. Game changer. Pioneer. TRC has long set the bar for clients who require more than just engineering, combining science with the latest technology to devise innovative solutions that stand the test of time. From pipelines to power plants, roadways to reservoirs, schoolyards to security solutions, clients look to TRC for breakthrough...
-
Medicinal Chemistry
1 week ago
san diego, United States Light Horse Therapeutics Full timeLight Horse Therapeutics is a small molecule drug discovery company based in San Diego, employing tools from chemical and computational biology, in conjunction with precision genome editing methods to identify functional/ligandable sites on high value oncology protein targets for therapeutic intervention. Light Horse therapeutics was founded by leading...
-
Medicinal Chemistry
1 week ago
san diego, United States Light Horse Therapeutics Full timeLight Horse Therapeutics is a small molecule drug discovery company based in San Diego, employing tools from chemical and computational biology, in conjunction with precision genome editing methods to identify functional/ligandable sites on high value oncology protein targets for therapeutic intervention. Light Horse therapeutics was founded by leading...
-
Medicinal Chemistry
1 week ago
San Diego, United States Light Horse Therapeutics Full timeLight Horse Therapeutics is a small molecule drug discovery company based in San Diego, employing tools from chemical and computational biology, in conjunction with precision genome editing methods to identify functional/ligandable sites on high value oncology protein targets for therapeutic intervention. Light Horse therapeutics was founded by leading...
-
Principal Data Scientist
4 days ago
San Diego, United States MAXIMUS Full timeDescription & Requirements Maximus is seeking a Principal Data Scientist to collaborate with product design and engineering teams to develop an understanding of needs. The candidate will research and devise innovative statistical models for data analysis. In this role, you will communicate findings to all stakeholders. The Principal Data Scientist will...
-
Principal Scientist, Translational Researcher
4 weeks ago
San Diego, California, United States Bristol-Myers Squibb Full timeTransforming Patients' Lives through ScienceBristol Myers Squibb is a leading pharmaceutical company dedicated to discovering and developing innovative treatments for patients with serious diseases. We are seeking a highly skilled Principal Scientist, Translational Research to join our team in San Diego, CA.About the Role:As a Principal Scientist,...
-
Technical Development Principal
2 months ago
San Francisco, United States Genentech Full timeThe Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech, a member of the Roche Group. The Opportunity A Principal /...
-
Technical Development Principal
3 days ago
San Francisco, United States Genentech Full timeThe Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech, a member of the Roche Group. The Opportunity A Principal /...
-
Principal Applied Scientist, AGI Foundations
2 months ago
San Francisco, United States Amazon Full timePrincipal Applied Scientist, AGI FoundationsJob ID: 2673976 | Amazon.com Services LLCAs a Principal Scientist within Alexa, you are a trusted part of the technical leadership. You bring business and industry context to science and technology decisions. You set the standard for scientific excellence and make decisions that affect the way we build and...
-
Principal Scientist, Discovery Data Science
1 month ago
San Diego, California, United States Johnson & Johnson Full timeJob Title: Principal Scientist, Discovery Data ScienceJohnson & Johnson Innovative Medicine is seeking a highly skilled Principal Scientist, Discovery Data Science to contribute to the advancement of Artificial Intelligence/Machine Learning (AI/ML) for Drug Discovery. The ideal candidate will have a strong background in data science, AI/ML, and computational...
-
San Diego, California, United States Bristol-Myers Squibb Full timeTransforming Patients' Lives through ScienceBristol-Myers Squibb is a leading biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that transform patients' lives. We are seeking a highly skilled and experienced Translational Medicine Senior Principal Scientist to join our team.Key Responsibilities:Design and...
Senior Scientist/Principal Scientist
2 months ago
In this role, you will:
- Lead Metabolite Profiling: Oversee the identification and characterization of metabolites and conduct enzymology studies.
- Drive Innovation: Provide scientific and strategic input to guide medicinal chemists in optimizing chemical series and solving complex problems.
- Collaborate Cross-Functionally: Work closely with team members to ensure innovative solutions and successful project outcomes.
- Design and Manage Studies: Plan and execute in vitro soft-spot and tox species selection MetID studies and definitive in vivo MetID studies.
- Execute Experimental Work: Perform laboratory experiments and manage biotransformation studies conducted at CROs.
- Analyze and Present Data: Interpret mass spectra, prepare data summaries, and present findings to project teams and management.
- Contribute to Regulatory Documentation: Author and support regulatory reports and documents to facilitate clinical development.
Requirements:
- Education & Experience: PhD in Organic Chemistry, Drug Metabolism, Pharmacokinetics, Pharmaceutical Sciences, or a related discipline with 7+ years of industry experience; alternatively, MS/BS with 12+ years of relevant experience.
- Expertise: Extensive knowledge in drug metabolism, in vitro enzyme kinetics, ADME assays, and LC/MS bioanalytical methodologies.
- Biotransformation Studies: Proven experience in designing, executing, and reviewing biotransformation studies.
- Regulatory Knowledge: Understanding regulatory guidance related to biotransformation, including MIST, with experience in preparing biotransformation documents for regulatory submissions is considered a plus.
Core Competencies:
- Communication Skills: Exceptional written and verbal technical communication abilities.
- Leadership & Influence: Proven ability to lead, guide, and influence teams in decision-making processes.
- Collaboration: Strong collaborative skills with the ability to build and maintain relationships across internal scientific functions and the broader scientific community.
- Autonomy & Teamwork: Capability to work independently and collaboratively within a multidisciplinary team setting.
- Data-Driven Analysis: Passion for data-driven analysis with a solid understanding of business-of-science thinking.
- Adaptability: Ability to excel in a fast-paced, highly matrixed environment.
- Technical Expertise: Deep knowledge of DMPK, biotransformation, enzymology, and DDI prediction strategies.
- Track Record: Demonstrated success in leading studies that support IND filings and contribute to drug discovery.
- CRO Management: Proficiency in managing CROs and a strong grasp of relevant regulatory guidance.
The ideal candidate will have strong expertise in mass spectrometry, experience with regulatory submissions, and a proven track record of working effectively in a team environment.
If you are a highly motivated individual with a passion for DMPK and drug development, apply today to join our innovative team
#J-18808-Ljbffr