Research Associate 1, MS
4 weeks ago
Essential Duties
1. Recommends the design and implementation of procedures and protocols under the direction of a higher-level authority. 2. Investigates, analyzes, and reaches preliminary scientific conclusions related to research planning 3. Ensures data results are compiled, analyzed, and presented properly. 4. Analyzes, develops and interprets scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports. 5. Performs independent research and laboratory techniques and participates in experimental research planning. 6. Interacts with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory. 7. Interacts with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and to keep abreast of product information and developments. 8. May perform other duties as assigned.
Required Education and Experience
Master's Degree in a scientific discipline and one year experience or an equivalent combination of education and demonstrated experience.
Background Check Requirements
All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.
Position Focus:
Carries out research assignments as part of a team of investigators in a multi-faceted research project requiring specialized experimental methods. Independently performs experiments and laboratory techniques. Trains incoming laboratory personnel (undergraduate, postgraduate, graduate students and postdoctoral associates) in complex experimental procedures and methods, and is the contact person for modifications, updates and renewals of laboratory Institutional Animal Care & Use Committee (IACUC) mouse protocol, and Environmental Health & Safety (EH&S) modifications, updates and renewals. Oversees daily lab operations related to the projects in the laboratory. Conducts research requiring specialized techniques, including: mouse colony management (including genotyping); breeding and tracking of genetically modified mice; the preparation of genetically modified human and mouse cell lines via genome editing; liver subset cells' isolation, collection and analysis of mouse tissues (with a focus in liver) using molecular, microscopic and related techniques; preparation of samples for analyses via confocal and super resolution microscopy and analysis of gene expression via bulk and single-cell RNA-sequencing; CRISPR screens in cell lines. Bioinformatic skills or willing to learn them for analysis of next generation sequencing data. Train incoming lab personnel in experimental methods developed in our laboratory. Analyzes and interprets scientific results. Presents reports of results at regular laboratory meetings.
Posting Disclaimer
The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.
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