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Research Technician II
4 months ago
School of Medicine
Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.
The Global Health Discovery Collaboratory (GHDC) Antibody Dynamics team at the Duke University Center for Human Systems Immunology is seeking a detail-oriented scientist to fulfill a key role as Research Technician II to support assessment of antibody biophysical measurements in an immune monitoring core lab. The assays performed by the Research Technician II include bio-layer interferometry and surface plasmon resonance methods to assess the antigen binding kinetic measurements of antibodies induced by vaccination in human clinical and pre-clinical vaccine trials for HIV, malaria, tuberculosis and other high priority global diseases.
Responsibilities
* Perform experiments to measure biomolecular interactions (i.e. binding kinetics and affinity) utilizing Surface Plasmon Resonance (SPR) and/or Bio-layer interferometry (BLI).
* Manage, track, and analyze data sets related to the evaluation of antibody responses to vaccines for human studies.
* Work together with the program manager, statistical team and laboratory staff ensure quality control of datasets.
* Work with the Quality Assurance Unit to maintain and perform work according to Good Clinical Laboratory Practices
* Collaborate with team members to develop custom tools for high throughput analysis of complex data sets.
* Perform other related laboratory duties as assigned by the Principal Investigator.
Education
* Bachelor's degree in Biochemistry or Biophysics or related Biological Science field.
* Master's degree in a related Biological Science field is a plus.
Experience
* Prior biochemistry or biophysics or biological laboratory experience.
* Experience in using SPR or BLI is a plus.
* Experience in working on R studio and/or Mathematica is a plus.
Skills and Abilities:
* Excellent communication skills and enjoy working in a team environment.
* Strong organizational and analytical skills.
* Knowledge of basic mathematical, data collection and research principles normally acquired through education and training.
* An interest in immunology, HIV, malaria, tuberculosis and probing antibody-protein interactions by biophysical methods and/or vaccine evaluation is highly desired.
Minimum Qualifications
Education
Work generally requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.
Experience
None required above education/training requirement. OR AN EQUIVALENT COMBINATIONOF RELEVANT EDUCATION AND/OR EXPERIENCE
Job Code: 00000951 RESEARCH TECHNICIAN II
Job Level: 08
Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
Nearest Major Market: Durham
Nearest Secondary Market: Raleigh
