Senior Global Commercial Lead, Hematology/Nephrology Pipeline

4 weeks ago

Boston, United States Alexion Pharmaceuticals, Inc. Full time

At Alexion, AstraZeneca Rare Disease, we are innovators, leaders, and collaborators. At the heart of everything we do is an intense desire to pursue the toughest challenges and truly change the world for people living with rare and devastating diseases.

Alexion's Global Marketing and Market Access team (GMMA) is an integrated strategy and operations team, with the core objective to develop disease and brand commercial and access strategies, as well as global marketing materials and negotiation strategies, while working closely with markets for implementation. The team diligently monitors the performance of the business and the effectiveness of our strategies, helping to position our brands for sustained long-term access and success. Additionally, the GMMA team delivers commercial strategies for our pipeline programs and establishes commercial marketing and access strategies for new product launches. Our unique culture thrives on collaboration, authenticity, creativity, and pushing boundaries in all that we do to advance patient care.

Key Responsibilities:

This role will be focused on IgAN portfolio strategy development and IgAN Ultomiris launch readiness; the role will also have an overall pipeline strategic accountability within Hem/Neph space.

More specifically:

* Oversee the strategic direction and execution of Hematology/Nephrology pipeline, ensuring alignment with company goals and regulatory/access requirements.
* Provide leadership in the development of a robust and diversified Hem/Neph pipeline, identifying opportunities for portfolio expansion and optimization within the therapeutic area.
* Stay informed of scientific advancements and unmet needs within Hem/Neph to inform decision-making and ensure the competitive positioning of the Hem/Neph pipeline.
* IgAN Global Commercialization Strategy Development: Formulate and implement global commercialization disease strategies, launch plans, and tactical plans for IgAN across all assets in development. Assist core markets in adapting and executing these strategies, ensuring global strategy is synchronized across functions to optimize business performance.
* IgAN Launch Planning: Collaborating with GPTs and cross-functional partners, accountable for ensuring organizational launch readiness both at the global and local level. Collaborate with Global Product Teams (GPTs) to devise and disseminate launch plans, ensuring seamless, strategically aligned launches.
* Engage with Global Product Team. Key activities include:
* Delivery of the Target Product Profile (TPP)
* Concluding pivotal and pediatric studies, as well as post-marketing requirements
* Monitoring program timelines, milestones, risks, and deliverables
* Overseeing submissions, approvals, and launches across the globe
* Creating strategies for value generation
* Delivery of governance-approved business cases within tolerance on time, cost, and quality, working with functional management as required to resolve issues.


* Input into MTP to ensure that countries are resourced appropriately.
* Guarantee first-in-class launches across all Markets with direct involvement with early launch markets.
* Develop Int'l launch strategy & plan incl. commercial forecasting.
* Conduct launch readiness reviews as per standard timing, starting with L-24.
* Develop launch kits, materials, training, proposed KPIs, tracking tools, and dashboards.
* Support countries with functional needs like pricing, market access or regulatory strategy, market shaping, local studies or evidence generation, etc.

The successful candidate must be a strong matrix leader, good communicator, and a well-rounded global commercial leader, with a specific appetite for shaping and implementing brand strategy. Clear strategic thinking with the ability to lead and demonstrate passion for the brand is required.

You will need to have:

* Bachelor's degree in Business, Medical or Life sciences degree
* 15+ years pharmaceutical commercial experience
* Expertise in renal , Hematology, and / or rare diseases
* Broad commercial experience including pre-launch and launch, strategic Consultancy experience in pharma preferred
* In-countries commercial / access leadership roles (BUD/Head of Access)
* Proven experience and knowledge of a broad base of external customers including patients, prescribers, payers and providers
* Experience leveraging clinical data to shape brand strategies and lifecycle planning
* Experience with revenue forecasting, budget/expense management, business case development and management/ communication of brand performance. Evidence of developing compelling business cases
* Experience working with medical, clinical professionals, scientific societies and patient advocacy groups
* Sufficient understanding of technical risks and the implications for the commercial aspects to future brands
* An in-depth technical knowledge in all commercialization aspects (commercial, market access and medical) and most preferably strong knowledge of the disease areas of interest
* Strong knowledge of business and financial planning, high level of financial acumen and attention to detail
* Broad cultural orientation, with experience of working outside local market or in an international context.
* Success in market shaping activities to establish the unmet need in a disease area.
* Successful track record in leading high performing cross functional teams.
* Successful track record in working and delivering in a highly matrixed global environment.
* Confident leader comfortable communicating and engaging across all levels in the organization, as well as maintaining calm composure, presenting, and influencing at senior levels
* Strong Project Management skills and the ability to coordinate and drive complex projects through the matrix

Desirable Skills/Experience:

* An advanced degree (MBA, MSc or PhD) is preferred

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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