Senior Scientist, DMPK

1 week ago


chicago, United States TalentCraft Full time

Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)


Role Summary

Seeking a Senior Scientist to advance our research in Drug Metabolism/Pharmacokinetics (DM/PK). This key position will drive in vivo evaluations of therapeutic candidates, focusing on pharmacokinetics, metabolism, and bioavailability of novel compounds. The role requires a strong DM/PK background, extensive in vivo testing experience, and the ability to design studies and influence drug discovery strategy.


Primary Responsibilities

- Independently design and conduct in vivo pharmacokinetic studies to assess drug candidates' metabolism and bioavailability using various animal models, with an emphasis on mouse models for cancer therapeutics.

- Develop experimental protocols and oversee the IACUC review/approval process.

- Collaborate with interdisciplinary teams, including chemists and biologists, to integrate DM/PK data across the drug discovery and development stages.

- Manage and mentor laboratory technicians, guiding experimental techniques and ensuring smooth lab operations.


Qualifications

-Education: M.S. or Ph.D. in Pharmacokinetics, Drug Metabolism, Pharmacology, or a related field.

-Experience:

- M.S. with 10+ years of relevant postdoctoral DM/PK experience or Ph.D. with 5+ years; industry experience is preferred.

- Extensive experience in in vivo pharmacokinetics, including study design, execution, and data analysis.

- Skilled in in vivo procedures, such as administering test molecules to mice, tissue collection and processing, and histology techniques, including H&E staining.

- Proficient in data analysis tools like WinNonlin, Phoenix, or similar PK/PD modeling software.

- Demonstrated scientific contributions, including peer-reviewed publications.


Core Competencies

- Problem-solving ability with a hands-on approach in a laboratory setting.

- Strong team collaboration skills within a multidisciplinary research environment.

- Excellent communication skills, with proficiency in presenting complex data to various stakeholders.



  • Chicago, United States TalentCraft Full time

    Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)Role SummarySeeking a Senior Scientist to advance our research in Drug Metabolism/Pharmacokinetics (DM/PK). This key position will drive in vivo evaluations of therapeutic candidates, focusing on pharmacokinetics, metabolism, and bioavailability of novel compounds. The role requires a strong DM/PK...


  • Chicago, United States TalentCraft Full time

    Position: Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)Role SummarySeeking a Senior Scientist to advance our research in Drug Metabolism/Pharmacokinetics (DM/PK). This key position will drive in vivo evaluations of therapeutic candidates, focusing on pharmacokinetics, metabolism, and bioavailability of novel compounds. The role requires a strong...


  • chicago, United States TalentCraft Full time

    Position: Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)Role SummarySeeking a Senior Scientist to advance our research in Drug Metabolism/Pharmacokinetics (DM/PK). This key position will drive in vivo evaluations of therapeutic candidates, focusing on pharmacokinetics, metabolism, and bioavailability of novel compounds. The role requires a strong...


  • chicago, United States TalentCraft Full time

    Position: Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)Role SummarySeeking a Senior Scientist to advance our research in Drug Metabolism/Pharmacokinetics (DM/PK). This key position will drive in vivo evaluations of therapeutic candidates, focusing on pharmacokinetics, metabolism, and bioavailability of novel compounds. The role requires a strong...


  • Chicago, Illinois, United States AbbVie Full time

    About the RoleWe are seeking a highly skilled Senior Scientist to join our Quantitative, Translational and ADME Sciences (QTAS) group at AbbVie. As a key member of our team, you will be responsible for providing mechanistic and translational modeling and project support in all disease areas, informing decision-making in both small and large molecule projects...


  • Chicago, Illinois, United States AbbVie Full time

    Job DescriptionAbbVie is seeking a highly skilled Senior Scientist to join our Quantitative, Translational and ADME Sciences (QTAS) group. The ideal candidate will have expertise in mechanistic and translational modeling, with a strong background in PK/PD modeling and project support.Key Responsibilities:Develop and implement innovative, quantitative...

  • Senior Food Scientist

    4 weeks ago


    Chicago, Illinois, United States Indenovo Global Search & Selection Full time

    Job Title: Senior Food ScientistJob Summary:We are seeking a highly skilled Senior Food Scientist to join our team at Indenovo Global Search & Selection. As a Senior Food Scientist, you will be responsible for developing new beverages, managing development, research, formulation, and duplication of new products from conception to shelf, and performing lab...

  • Scientist

    1 month ago


    north chicago, United States Planet Pharma Full time

    Scientist IIONSITE – 100% of the timeDMPKsmall groupwork is increasingbiologics, large molecules, some small moleculeproficiency in HPLC is essentialtriple quant and LCMS expfamiliar with large moleculesexp with characterizationexp with sample prepinstrumentation: Agilent seriesYears of exp: 5LCMS – will not consider withoutproficiency in HPLC is...

  • Scientist

    1 month ago


    North Chicago, United States Planet Pharma Full time

    Scientist IIONSITE – 100% of the timeDMPKsmall groupwork is increasingbiologics, large molecules, some small moleculeproficiency in HPLC is essentialtriple quant and LCMS expfamiliar with large moleculesexp with characterizationexp with sample prepinstrumentation: Agilent seriesYears of exp: 5LCMS – will not consider withoutproficiency in HPLC is...

  • Senior Application

    7 days ago


    Chicago, United States CPS, Inc. (Food & Beverage Division) Full time

    Senior Application / Technical Service ScientistThe duties and responsibilities of the Senior Application / Technical Service Scientist will include:Help build the organization s technical understanding relating ingredient functionality to performance in food and beverage applications / productsWorking cross-functionally with internal and external product...

  • Senior Application

    3 days ago


    Chicago, United States CPS, Inc. (Food & Beverage Division) Full time

    Senior Application / Technical Service ScientistThe duties and responsibilities of the Senior Application / Technical Service Scientist will include:Help build the organization s technical understanding relating ingredient functionality to performance in food and beverage applications / productsWorking cross-functionally with internal and external product...


  • Chicago, Illinois, United States Metropolitan Water Reclamation District of Greater Chicago Full time

    Job SummaryUnder general direction, the Senior Environmental Soil Scientist will conduct research, provide technical assistance on processing, regulatory monitoring and reporting, and supervise staff related to support of beneficial reuse of biosolids.Key ResponsibilitiesAssigns, supervises and reviews the work of subordinates.Coordinates Environmental...


  • chicago, United States TalentCraft Full time

    Senior Scientist, Bioanalytical ChemistryRole OverviewWe are currently partnering with a smaller sized pharmaceutical company in their search for a Senior Scientist in Bioanalytical Chemistry to join their R&D team. The ideal candidate will have deep expertise in mass spectrometry and high-throughput analytical methods for biological sample analysis. This...


  • Chicago, United States TalentCraft Full time

    Senior Scientist, Bioanalytical ChemistryRole OverviewWe are currently partnering with a smaller sized pharmaceutical company in their search for a Senior Scientist in Bioanalytical Chemistry to join their R&D team. The ideal candidate will have deep expertise in mass spectrometry and high-throughput analytical methods for biological sample analysis. This...


  • Chicago, Illinois, United States AbbVie Full time

    Job SummaryAbbVie is seeking a highly skilled Senior Analytical Scientist to join our Parenteral Product Development Science & Technology (PDS&T) team. As a key member of our Analytical Development group, you will be responsible for developing and optimizing analytical methods for our pipeline products.Key Responsibilities:Develop and validate analytical...

  • Senior Data Scientist

    4 months ago


    Chicago, United States United Airlines Full time

    As a Senior Data Scientist specializing in Statistics, your role will involve developing innovative approaches and methods to solve management problems using quantitative analysis, statistical modeling, machine learning, and forecasting techniques. You will be tasked with tackling large, complex problems by leveraging big data and statistical principles,...


  • Chicago, Illinois, United States Yash Technologies Full time

    Key ResponsibilitiesAs a Senior Data Scientist Manager at Yash Technologies, you will lead and manage a team of data scientists and machine learning engineers to develop and implement advanced machine learning models using Azure ML.Key responsibilities include:Providing mentorship and guidance to junior team members, fostering a collaborative and innovative...


  • Chicago, Illinois, United States CPS Full time

    Job Summary:CPS is seeking a highly skilled Senior Materials Scientist to join our R&D team. In this role, you will be responsible for leading programs to develop structural-property relationships of new packaging materials, including water-soluble flexible packaging.Key Responsibilities:Lead cross-functional teams in the evaluation of new materials and...


  • Chicago, Illinois, United States CPS Full time

    Job SummaryCPS is seeking a highly skilled Senior Polymer Research Scientist to lead the development of novel water-soluble polymeric systems within or tangential to the PVOH space.Key ResponsibilitiesLead synthesis and evaluation of novel water-soluble polymeric systems within or tangential to the PVOH spaceDevelop and enhance understanding of key structure...


  • Chicago, Illinois, United States AbbVie Full time

    Job SummaryAbbVie is seeking a highly motivated and collaborative Senior Scientist to lead the formulation design for small molecule development candidates within the AbbVie pipeline. The ideal candidate will have a proven track record in the design, characterization, and understanding of long-acting injectable (LAI) formulations and processes.Key...