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Bio-conjugation Scientist

2 months ago


san francisco, United States eTeam Full time

Title:: Bio-conjugation Scientist

Location: South San Francisco, CA 94080

Duration: 12 Months

Pay Rate: $66/hr


Responsibilities:

This is a Bio-conjugation Scientist role with MRL SSF Discovery Chemistry group.

Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at our South San Francisco, CA site.

• The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.

• Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.

• Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.


Specific responsibilities will include:

• Perform bioconjugations of linker-payload combinations to antibodies with Client on in-house established methods

• Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)

• Acquisition and interpretation of analytical data such as LC/MS.


Minimum 8 years of relevant industry experience is needed with BS/MS and 5 years with PHD.

Required: Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.


Qualifications:

This is a Bio-conjugation Scientist role, so please advertise it as per this title to get the relevant resumes and candidates’ applications.

Education Requirement:

• Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.


Experience and Skills Required:

• Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.

• Nice to have skills: Biologics analytic experience, purification techniques.

• Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.

• Personality: Team player, Adheres to timeline, Communicative and collaborative.


Note: Onsite, 100% Lab based role. Possibility of extension.