Senior Lab Operations

2 months ago

Cambridge, United States Repertoire Immune Medicines Full time
Job DescriptionJob DescriptionSenior Lab Operations & Facilities AssocaiteCompany Overview
Repertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded on the belief that understanding the repertoire of T cell receptor (TCR)-antigen immune synapses that maintain health and drive disease represents one of the greatest opportunities for innovation in medical science. Repertoire scientists created and developed the DECODETM platform, which allows in-depth characterization of TCR-antigen pairs, and the ability to deploy this information in the form of novel targeted immune medicines to fundamentally reprogram the immune system to kill tumors or induce immune homeostasis.

From its sites in Cambridge, Massachusetts and Zurich, Switzerland, Repertoire’s team is advancing a pipeline of DECODE-enabled immune medicines, such as TCR bispecifics and mRNA cancer vaccines for treatment of solid tumors and mRNA tolerizing vaccines for treatment of autoimmune diseases.

Repertoire was founded by Flagship Pioneering and is supported by a strong investor base. In addition, the company recently entered into a strategic partnership with Bristol Myers Squibb to develop tolerizing vaccines for up to three autoimmune diseases. 

On site 5 days per week in Cambridge, MA

Role Overview
Reporting to the Associate Director of Lab Operations and Facilities, the Senior Lab Operations and Facilities Associate will act as a primary liaison between R&D and Lab Operations. This role is responsible for ensuring that lab activities are not disrupted, that equipment is well maintained, and that research scientists' operational needs are supported. The selected candidate will work with a multi-disciplinary team to develop, implement and successfully manage the robust alarm monitoring and building controls system at Repertoire. (S)he/they will support Repertoire programs through strong communication, commitment to meeting deadlines, strong organizational skills, and a solid understanding of the activities, processes, and policies necessary for a safe, efficient, and compliant laboratory environment. 

Key Responsibilities
  • Performs scheduled, routine lab activities such as removal of biological waste bins, emptying of tissue culture waste traps, glass washing/autoclaving, defrosting freezers, sanitization of equipment, monitoring of compressed gas supply, and general upkeep of all lab instrumentation.
  • Manages all aspects of shipping and receiving.
  • Supports and tracks waste management (i.e., collection of biowaste, chemical waste and sharps containers).
  • Ensures general maintenance, calibration, troubleshooting, repair, installation, qualification, and configuration of equipment and instrumentation, as well as general maintenance and upkeep of the office premises.
  • Maintains the operational consumables program; ordering based on predetermined minimum limits, organizing consumables based on workflow locations, and labeling lab supplies and electronically tracking them. Works with scientists and the Associate Director of Facility and Lab Operations to support efficient, timely, and cost-effective ordering of critical lab supplies.
  • Assists with inventory management for Lab Operations (i.e., equipment inventory, chemical inventory).
  • Supports purchase order requisitions, work requests, and associated files, as well as tracking, shipping, and receiving of mail and packages.
  • Promotes a continuous improvement environment by observing daily workflow and identifying ways to streamline procedures.
  • Encourage a safe work environment by adhering to and enforcing all safety procedures and identifying potential hazards.
  • Identifies and communicates technical issues regarding lab assets with R&D leadership.
  • Works with a Team to provide full-time emergency on-call response.
  • Builds and maintains professional relationships with common vendors and courier services to support efficient and effective support for Repertoire service and community needs.
Qualifications/Experience
  • Associate or bachelor’s degree with 2 to 6 years of experience as a lab technician or operations assistant, preferably in the biotechnology industry.
  • Strong computer skills with proficiency in Microsoft Office, particularly in Word and Excel. Facile use of web-based applications that support asset and consumables management.
  • Strong communication skills and the ability to interact with all levels of staff and external contacts in a fast- paced and changing environment.
  • Excellent organizational and time managements skills and the ability to simultaneously handle a variety of responsibilities with minimal supervision.
  • Strong mechanical skills; can plumb incubators, change out filters in the water filtration systems, and use a manual to troubleshoot instrumentation issues.
  • Demonstrated experience in executing initiatives dedicated to laboratory safety and associated regulatory guidelines.
  • Training/certifications in DOT Ground Transportation, Hazmat, General Lab Safety and CPR/AED/First Aid preferred.
Work Environment/Physical Requirements
  • Ability to perform the physical demands of the role, including lifting moderately heavy boxes and office equipment (up to 50 pounds) and trash, prolonged standing, moving gas tanks, etc. May also require work in dusty and dirty environments and work with noisy machinery such as air compressors and HVAC equipment.
  • Specific and uncompromised vision abilities are required for the essential functions of the job.


Repertoire is committed towards social responsibility and developing an inclusive culture. Much as the power of the immune system lies in the diversity of T and B cells, our work requires the creativity and ingenuity of a diverse workforce.  We believe in actively pursuing equity in all facets of the work experience at Repertoire.  We will continue to educate ourselves about the inequities and barriers present in our society and take action as a company where we can make a difference.
Repertoire is proud to be an Equal Opportunity Employer.
Recruitment & Staffing Agencies: Repertoire Immune Medicines (“Repertoire”) does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Repertoire or its employees is strictly prohibited unless contacted directly by Repertoire’s internal Human Resources team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Repertoire, and Repertoire will not owe any referral or other fees with respect thereto.

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