Process Development Scientist
3 months ago
Garuda Therapeutics, a biotechnology company focused on developing off-the-shelf human hematopoietic stem cell-based cellular therapies, is seeking a highly motivated Scientist to join its growing team. The full-time role will be a key member of the process development team, focusing on scaling up pluripotent stem cell (iPSC) expansion and differentiation in bioreactors, as well as implementing closed-system cell processors (e.g., cell washers, magnetic separation instruments, etc.) into a clinical manufacturing process. Under the supervision of the Executive Director of Technical Operations and working closely within the R&D Department, the ideal candidate will be responsible for the day-to-day execution, analyzing data and presenting results of projects relevant to the core focus of the Garuda Therapeutics. This position will be located onsite in Watertown, MA or Cambridge, MA and requires the ability to work out of either site as needed.
Key Responsibilities Include:
- Culturing human pluripotent stem cells in various conditions, aiming to scale up expansion and differentiation
- Validation and qualification activities to support the qualification of single-use bioreactors
- Implementation of closed-system cell processing systems
- Suggests new, innovative solutions to problems
- Collaborating internally with Garuda team and Manufacturing, train colleagues in new techniques and maintain relationships with external scientific partners
Required Qualifications:
- PhD with 1-3+ years, MS with 5-7+ years, or BS with 7+ years of related experience
- Prior experience working in the biotech/pharmaceutical industry is required
- Experience with human pluripotent stem cell culture is required
- Experience with cell culture in bioreactors and closed-system cell processing systems
- Demonstrated excellence in planning, executing, and analyzing experiments
- Critical thinking and independence, ability to troubleshoot, solve difficult problems, and develop process improvements
- Attention to detail and careful record-keeping
- Excellent organizational skills and ability to manage multiple projects
- Excellent oral and written communication skills, able to write technical reports and protocols
- Flexible team player excited to collaborate with internal and external partners
- Highly self-motivated and flexibility in working schedule to accommodate weekend work if necessary
Preferred Qualifications:
- Experience with DOE and JMP
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