Senior Scientist or Principal Scientist

1 month ago


South San Francisco, United States Trova Talent Full time
Job DescriptionJob DescriptionMy client is seeking a highly motivated, self-driven, collaborative and experienced individual  with strong iPSC and cell engineering background. The successful candidate will be accountable for establishing control laboratory operation for iPSC seed stock production. This role requires dedication to drive science, ability to multitask, excellent communication and organizational skills, attention to detail, and the ability to work independently as well as collaboratively with a multidisciplinary team of scientists and research associates.

Specific responsibilities include, but are not limited to:
  • Cell engineering of primary T cells, iPSC and iPSC-derived T cells using various gene delivery methods, including but not limited to CRISPR KO/KI, lentivirus/gamma retrovirus transduction.
  • Support the therapeutic development of T cell products derived from iPSCs.
  • Design and execute experimental plans for the development and optimization of the hypoimmune iPSC platform.
  • Process development of iPSC multiplex editing and single cell cloning process. Establish in-house control laboratory operation to manufacture genetically modified iPSC seed stock for pipeline.
  • Write SOP, technical reports, and develop appropriate documentation for processes.
  • Analyze, interpret, and effectively present data at team meetings

Requirements and Experiences
  • A minimum of 2 years postgraduate experience in relevant roles in academia/industry, preferably in allogeneic cell therapy space
  • Strong hands-on experience with iPSC culture, gene editing and single cell cloning.
  • Knowledge of GxPs, past experience in process development or GMP operation is a plus.
  • Strong organizational skills and an ability to prioritize effectively to deliver results within established timelines.
  • Strong verbal and written communication skills are critical in the fast-face and collaborative working environment.
  • Demonstrated accountability and flexibility to change project objectives quickly and enthusiastically.

Powered by JazzHR

FsdAUuU0gS


  • Principal Scientist

    1 month ago


    South San Francisco, United States Life Science People Full time

    Job Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...

  • Principal Scientist

    4 days ago


    South San Francisco, United States Life Science People Full time

    Job Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...

  • Principal Scientist

    2 weeks ago


    South San Francisco, United States Life Science People Full time

    Job Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...


  • San Diego, California, United States Novartis Full time

    AD/Sr. Principal Scientist - CADDThe Computer-Aided Drug Discovery (CADD) group in San Diego is seeking an AD/Senior Principal Scientist to join our talented and innovative drug discovery team.Initiate drug discovery efforts by proposing novel targets / modalities, evaluating target druggability and executing in silico hit generation, triage and expansion...


  • San Diego, California, United States Oculus Search Partners Full time

    Principal Scientist, Peptide Protein Chemistry Direct HirePrincipal Scientist, Peptide Protein Chemistry This BioPharma is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options.Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein...


  • San Francisco, United States Amgen Full time

    **HOW MIGHT YOU DEFY IMAGINATION?** If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering...

  • Sr. Scientist

    2 weeks ago


    San Diego, United States Meet Full time

    Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...

  • Sr. Scientist

    5 days ago


    San Diego, United States Meet Full time

    Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...

  • Sr. Scientist

    2 weeks ago


    San Diego, United States Meet Full time

    Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...


  • San Diego, United States Meet Full time

    Start-Up Biotech located in San Diego, is searching for a Senior/Principal Scientist to join their team on a fulltime basis. RequirementsBe able to run HPLC (High-performance liquid chromatography)Recent small-molecule experienceAnalytical research Will be joining a small close-knit team, working on exciting science with like-minded individuals!


  • San Diego, United States Meet Full time

    Start-Up Biotech located in San Diego, is searching for a Senior/Principal Scientist to join their team on a fulltime basis. RequirementsBe able to run HPLC (High-performance liquid chromatography)Recent small-molecule experienceAnalytical research Will be joining a small close-knit team, working on exciting science with like-minded individuals!


  • San Diego, United States Meet Full time

    Start-Up Biotech located in San Diego, is searching for a Senior/Principal Scientist to join their team on a fulltime basis. RequirementsBe able to run HPLC (High-performance liquid chromatography)Recent small-molecule experienceAnalytical research Will be joining a small close-knit team, working on exciting science with like-minded individuals!

  • [Senior] Scientist

    4 weeks ago


    South San Francisco, United States Y-Trap Full time

    Job DescriptionJob DescriptionY-Trap is seeking a highly motivated and fast-moving [Senior] Scientist – Immunology, who will be responsible for design and hands-on execution of in vitro experiments to advance the discovery and development of multifunctional fusion proteins for cancer immunotherapy.About us: Y-Trap is a startup in South San Francisco...

  • Senior Scientist

    2 weeks ago


    South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full time

    BEPC has an open position for a Scientist 1 (Protein Expression and Purification, Contract role)!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $43-$50/hr. + Medical, Dental, Vision and Life InsuranceThe departments of BioMolecular Research and Structural Biology, within the Protein Sciencesorganization at Genentech...

  • Senior Scientist

    5 days ago


    South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full time

    BEPC has an open position for a Scientist 1 (Protein Expression and Purification, Contract role)!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $43-$50/hr. + Medical, Dental, Vision and Life InsuranceThe departments of BioMolecular Research and Structural Biology, within the Protein Sciencesorganization at Genentech...

  • Scientist

    5 days ago


    South San Francisco, United States Aequor Full time

    Job Title: Oligonucleotide Scientist-2Location: South San Francisco, CADuration: 1 yearThe Position:We are seeking a creative, self-motivated, collaborative Contractor/Scientist-II to join the Department of Protein Chemistry (PC) – ProteinSciences (PS).We are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our...

  • Scientist

    5 days ago


    South San Francisco, United States Aequor Full time

    Job Title: Oligonucleotide Scientist-2Location: South San Francisco, CADuration: 1 yearThe Position:We are seeking a creative, self-motivated, collaborative Contractor/Scientist-II to join the Department of Protein Chemistry (PC) – ProteinSciences (PS).We are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our...

  • Scientist

    5 days ago


    South San Francisco, United States Aequor Full time

    Job Title: Oligonucleotide Scientist-2Location: South San Francisco, CADuration: 1 yearThe Position:We are seeking a creative, self-motivated, collaborative Contractor/Scientist-II to join the Department of Protein Chemistry (PC) – ProteinSciences (PS).We are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our...


  • San Diego, United States Meet Full time

    Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...


  • San Diego, United States Meet Full time

    Meet's partnered with an exciting and growing biotech in San Diego for a Senior Scientist / Principal Scientist Analytical Development!You'll be responsible for designing, executing, and reporting on the analytical development of small molecule chemistry experiments, degradation pathways, characterization, and stabilization techniques for ophthalmic and...