[Senior] Scientist
4 weeks ago
About us: Y-Trap is a startup in South San Francisco developing novel fusion proteins for cancer immunotherapy, founded by Johns Hopkins and Stanford scientists. While current immunotherapies aim to activate and expand T cells by blocking immune checkpoints, they do not correct the immunosuppressive & tumor-promoting phenotypes of immune cells that dominate in the tumor. Y-Trap has utilized its versatile computational engineering platform to develop a portfolio of antibody-ligand traps (“Y-traps”) designed to counteract the determinants of these tumor-promoting immune cell phenotypes. Y-Trap is currently advancing its lead programs towards first-in-human clinical studies.
In this role, you will:
- Independently design, execute, and interpret experiments to support the development of immuno-modulating fusion proteins.
- Support the management of outsourced activities such as protein expression and in vivo toxicology.
- Support wet-lab protein engineering efforts.
- Strong expertise in a variety of immunological assays, cell culture and immune cell characterization. You love being in the lab and are great at flow cytometry. You're comfortable generating reporter cell lines, running an ELISA, and bringing a new assay online.
- Self-driven and resourceful. You're excited to learn new skills when needed, with a mentality to do whatever it takes to get the job done in a small team with a lot of autonomy.
- You may have a PhD in immunology (or a related field), or have gained equivalent experience working in industry.
- Experience accomplishing the above objectives in a fast-paced startup environment.
- Experience with protein engineering techniques (e.g., yeast display).
- Knowledge of biologics drug development, such as managing outsourced IND-enabling toxicology studies.
Y-Trap is based in South San Francisco, CA and offers competitive salary, benefits, and stock options. This is not an entry-level position, but candidates of varying seniority are encouraged to apply. Seniority and compensation will be commensurate to experience.
Powered by JazzHR
5iayevaZub
-
Senior Scientist
2 weeks ago
South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full timeBEPC has an open position for a Scientist 1 (Protein Expression and Purification, Contract role)!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $43-$50/hr. + Medical, Dental, Vision and Life InsuranceThe departments of BioMolecular Research and Structural Biology, within the Protein Sciencesorganization at Genentech...
-
Senior Scientist
5 days ago
South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full timeBEPC has an open position for a Scientist 1 (Protein Expression and Purification, Contract role)!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $43-$50/hr. + Medical, Dental, Vision and Life InsuranceThe departments of BioMolecular Research and Structural Biology, within the Protein Sciencesorganization at Genentech...
-
Senior Scientist I, Pathology
1 month ago
South San Francisco, California, United States BioSpace Full timeThe Precision Medicine organization within AbbVie is committed to driving translational research and clinical biomarker strategy for our pre-clinical and clinical stage programs.The Precision Medicne Pathology group within Precision Medicine supports projects from discovery through CDx assay development.We are seeking a highly motivated and experienced...
-
Principal Scientist
1 month ago
South San Francisco, United States Life Science People Full timeJob Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...
-
Principal Scientist
4 days ago
South San Francisco, United States Life Science People Full timeJob Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...
-
Principal Scientist
2 weeks ago
South San Francisco, United States Life Science People Full timeJob Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...
-
Associate Scientist
4 weeks ago
South San Francisco, California, United States Amgen Full timeThe Associate Scientist at Amgen conducts a variety of routine laboratory tasks and procedures. They assist with data collection and basic analysis under the supervision of more senior scientists.Key Responsibilities:Design and perform in vitro studies to assess the biology of novel targets and evaluate mechanisms of action of therapeutic...
-
Senior Data Scientist
2 days ago
San Francisco, United States Unreal Gigs Full timeJob DescriptionJob DescriptionCompany Overview: Welcome to the forefront of data-driven innovation! At our company, we're dedicated to leveraging the power of data to drive insights and empower decision-making. Our mission is to develop cutting-edge data science solutions that transform businesses and industries. Join us and be part of a dynamic team...
-
Senior Scientist
1 month ago
San Diego, California, United States Tentarix Biotherapeutics Full timeWe are led by a seasoned executive team with proven expertise in the field of multi-specific drug discovery.We are committed to hiring and retaining highly qualified and motivated team members who are passionate about making a difference for patients in the modern drug discovery landscape with our ground-breaking technology.The Senior Scientist Mammalian...
-
Senior Data Scientist
3 weeks ago
San Francisco, United States Unreal Gigs Full timeJob DescriptionJob DescriptionThe RoleWe are seeking a Senior Data Scientist to join us as one of the founding members of our team, focusing on developing innovative machine learning solutions to solve complex real-world problems for our clients.In this position, you will collaborate closely with the founders, engineering team, and clients to architect and...
-
Senior Scientist, Cell
1 month ago
San Diego, California, United States Pharmaron Full timeThe Senior Scientist will play a pivotal role by supporting in vivo studies to test cell and gene therapy treatments.The Senior Scientist serves as Study Director and is responsible for the oversight and conduct of in-vivo studies involving the testing of pharmaceutical compounds and cell and gene therapy.The Study Director functions as a key member of the...
-
Senior Data Scientist
20 hours ago
San Francisco, United States Xero Full timeAbout the Team The Data team is responsible for driving the adoption of data driven decision making across Xero - for both our internal users and our global audience of small business owners, bookkeepers and accountants. We create, manage and deliver a wide range of data services and products including core reporting, key data dimensions, extensible and...
-
Senior Data Scientist
2 days ago
San Francisco, California, United States Xero Full timeAbout the Team The Data team is responsible for driving the adoption of data driven decision making across Xero - for both our internal users and our global audience of small business owners, bookkeepers and accountants. We create, manage and deliver a wide range of data services and products including core reporting, key data dimensions, extensible and...
-
Senior Scientist, Statistical Genetics
2 days ago
South San Francisco, United States Maze Therapeutics Full timeThe Position: Translational Genomics team is looking for an exceptional Sr. Scientist in statistical genetics. Maze utilizes human genetics at all stages of drug development. You will design, lead and/or execute robust genetic association studies with the goal of identifying potential drug targets. You will also contribute to target validations and mechanism...
-
Associate Scientist II
1 month ago
South San Francisco, California, United States Collabera Full timeOperate and maintain analytical and preparative scale HPLC instrumentation.Purification of samples from medicinal chemistry projects on a milligram to gram scale by preparative HPLC.Maintain and troubleshoot NMR spectrometer under the guidance of senior scientists.Hands-on experience with analytical HPLC, preparative HPLC, mass spectrometry, and/or...
-
Senior Scientist, Statistical Genetics
5 days ago
South San Francisco, California, United States Maze Therapeutics Full timeThe Position:Translational Genomics team is looking for an exceptional Sr. Scientist in statistical genetics. Maze utilizes human genetics at all stages of drug development. You will design, lead and/or execute robust genetic association studies with the goal of identifying potential drug targets. You will also contribute to target validations and mechanism...
-
Senior Data Scientist
4 weeks ago
San Francisco, California, United States Unreal Gigs Full timeThe Role We are seeking a Senior Data Scientist to join us as one of the founding members of our team, focusing on developing innovative machine learning solutions to solve complex real-world problems for our clients. In this position, you will collaborate closely with the founders, engineering team, and clients to architect and implement end-to-end...
-
Senior Research Associate
19 hours ago
South San Francisco, United States Warman OâBrien Full timeSenior Research Associate/Associate Scientist | Onsite | Permanent | Competitive Salary Start Date: ASAP Location: South San Francisco  Whatâs it Like to Work Here?  My client, a growing biotech company at the forefront of biotechnology innovation, are in search of a senior research associate/ associate scientist. You will get...
-
Scientist I
2 days ago
San Francisco, California, United States Nurix Therapeutics Full timePositionWe are seeking a highly skilled and motivated immunologist to support Nurix's mission of targeting E3 ubiquitin ligases in the areas of immunology and oncology. This individual will work closely with our drug discovery project teams on optimization and characterization of novel compounds to evaluate their impact on immune cells and disease-relevant...
-
Senior Research Associate
4 weeks ago
South San Francisco, United States Warman O'Brien Full timeSenior Research Associate/Associate Scientist | Onsite | Permanent | Competitive Salary Start Date: ASAPLocation: South San FranciscoWhat’s it Like to Work Here? My client, a growing biotech company at the forefront of biotechnology innovation, are in search of a senior research associate/ associate scientist. You will get to work on the cutting edge of...