Scientist, Mass Spectrometry

3 weeks ago

South San Francisco, United States Parvus Therapeutics Full time
Job DescriptionJob DescriptionParvus Therapeutics Inc. 

Parvus Therapeutics Inc. is a privately held biopharmaceutical company developing Navacims™, a platform technology based on foundational research published in 2016 (Nature 530:434), to treat autoimmune diseases. Parvus’ mission is to shift the treatment paradigm toward Navacim™-directed immune regulation, avoiding non-specific immune suppression associated with current therapies. Parvus’ innovative approach has the potential to benefit millions of patients suffering from debilitating autoimmune diseases and other chronic inflammatory conditions. Parvus is advancing a pipeline of proprietary drug candidates for multiple autoimmune indications through preclinical development and into the clinic. Parvus’ leadership team is experienced in successful drug discovery, development, manufacturing, regulatory approval, and commercialization.

About Navacims™ 

Navacims™ are a novel first-in-class nanomedicine designed to treat autoimmune disease by selectively modulating disease-specific cellular responses without impairing normal immunity. Navacims™ specifically target and act only on disease causing effector T cells, delivering a signal that programs effector T cells to differentiate into regulatory T (Treg) cells specific for self-antigens relevant to the patient’s disease. These disease- or tissue-specific Treg cells induce immunological tolerance to block undesired immune responses to self-antigens, while maintaining normal immune surveillance and activity. 

The Position

We are seeking a Scientist to join the Protein Sciences and Process Development Group. The ideal candidate will conduct protein characterization mass spectrometry activities to support our pre-clinical and clinical programs with the Parvus technology platform. The individual should have extensive experience with protein characterization mass spectrometry, preferably peptide mapping, glycan analysis, glycobiology, and related protein post-translational modifications. Experience with in-vitro ELISA or activity assays is a plus.

Primary Responsibilities:
  • Primary contributor with protein characterizing mass spectrometry experiments, including maintaining the instrument, developing and performing experiments with an emphasis on intact mass, glycan analysis and peptide mapping studies.
  • Learn, develop, and perform in vitro protein and nanoparticle biophysical and binding characterization assays.
  • Prepare technical documents for transfer to contract manufacturers.
  • Work collaboratively in multi-functional groups to test drug substance critical quality attributes.
  • Contribute scientifically to the growing knowledge base of the Parvus technology platform.
  • Develop and execute detailed SOP’s that can be readily transferred to outside partners and document experiments in a lab notebook.
  • Present at team meetings, across Parvus, and with our business partners as needed to drive studies and provide analytical support to material production and manufacturing.
Requirements:
  • Ph.D. in biochemistry, chemistry, or a related discipline
  • 0-1 year of hands-on experience in industry. Experience with mass spectrometry, with an emphasis on glycan analysis and post-translational modification characterizations.
  • Expertise setting up, maintaining, and running LC/MS equipment independently or with minimal assistance is required.
  • Expert at solving technical challenges in protein characterization and assay development.
  • Experience with ELISAs is a plus.
  • Analytical problem solving and organizational skills are required to identify and resolve technical challenges.
  • Ability to work independently in the laboratory and in cross-functional teams.
  • Comfortable working collaboratively in a small, fast-paced environment.
  • Ability to quickly adjust to shifting project demands and priorities.
  • Good oral, written communication, and presentation skills.

Powered by JazzHR

Y8BuCaahfP

  • Senior/Principal Scientist in Translational Medicine Mass Spectrometry

    11 hours ago

    South San Francisco, United States SGA Inc. Full time

    Software Guidance & Assistance, Inc., (SGA), is searching for a Senior/Principal Scientist in Translational Medicine Mass Spectrometry for a CONTRACT assignment with one of our premier Pharmaceutical Services clients in San Francisco, CA. Responsibilities: ...

  • Principal Scientist in Translational Medicine Mass Spectrometry

    4 weeks ago

    South San Francisco, United States The Fountain Group LLC Full time

    Pay Range: $61-$101/hour Job Description: 12-month contract with the possibility of converting to permanent based on company needs and worker's performance. The Translational Medicine department informs clinical development of Client personalized therapeutics through establishment of biomarker strategies aimed to study biological pathways driving...

  • Senior/Principal Scientist in Translational Medicine Mass Spectrometry

    1 month ago

    South San Francisco, United States Compass Consulting Full time

    Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.  They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline. Job Overview: Our client's Translational...

  • Senior/Principal Scientist in Translational Medicine Mass Spectrometry

    4 weeks ago

    South San Francisco, United States HonorVet Technologies Full time

    The Translational Medicine department at Genentech informs clinical development of Client personalized therapeutics through establishment of biomarker strategies aimed to study biological pathways driving disease and by characterizing the mechanism of action of Client therapeutics. As a key member of the biomarker mass spectrometry laboratory, the ideal...

  • Senior/Principal Scientist in Translational Medicine Mass Spectrometry

    4 weeks ago

    South San Francisco, United States Compass Consulting Group Full time

    Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multi Spectrometry, Medicine, Scientist, Principal, Technology, Staffing

  • Mass Spectrometry Lab Manager

    7 hours ago

    South Plainfield, United States Scientech Laboratories, LLC Full time

    SCIENTECH LABORATORIES – MASS SPECTROMETRY LAB MANAGERThe Mass Spectrometry (MS) Lab Manager is responsible for establishing standard operating procedures (SOPs), developing methods and efficient work processes, managing lab workflow, personnel, and deliverables in a cGMP analytical chemistry laboratory responsible for testing OTC drug raw materials and...

  • Mass Spectrometry Lab Manager

    1 day ago

    South Plainfield, United States Scientech Laboratories, LLC Full time

    SCIENTECH LABORATORIES – MASS SPECTROMETRY LAB MANAGERThe Mass Spectrometry (MS) Lab Manager is responsible for establishing standard operating procedures (SOPs), developing methods and efficient work processes, managing lab workflow, personnel, and deliverables in a cGMP analytical chemistry laboratory responsible for testing OTC drug raw materials and...

  • Senior/Principal Scientist

    4 weeks ago

    San Francisco, United States R&D Partners Full time

    R&D Partners is seeking to hire a Senior/ Principal Scientist in Translational Medicine Mass Spectrometry (Contractor) in San Franciscon, CA. Your main responsibilities as a Senior/ Principal Scientist in Translational Medicine Mass Spectrometry (Con Scientist, Principal, Clinical Research, Spectrometry, Chemistry, Staffing

  • Senior Scientist, Pharmacokinetics

    8 hours ago

    South San Francisco, United States Amgen Full time

    **HOW MIGHT YOU DEFY IMAGINATION?** You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading...

  • Senior Scientist, Pharmacokinetics

    22 hours ago

    South San Francisco, United States Amgen Inc. Full time

    JOB ID: R-186633 LOCATION: US - California - South San Francisco WORK LOCATION TYPE: On Site DATE POSTED: Apr. 22, 2024 CATEGORY: Scientific SALARY RANGE: 131,588.00 USD - 150,335.00 USD HOW MIGHT YOU DEFY IMAGINATION? You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your...

  • Senior Scientist, Pharmacokinetics

    17 hours ago

    South San Francisco, United States BioSpace Full time

    Job DetailsHOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading...

  • Scientific Lead, Analytical and Mass-spectrometry

    1 month ago

    San Francisco, United States Lilly Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Research Associate

    4 weeks ago

    South San Francisco, United States Aequor Technologies LLC Full time

    Job Title: Research Associate Location: South San Francisco, CA Duration: 1 year contract Note: The hiring manager's target would be for someone in level I-II, but they could stretch to level III depending on their experience and skill set. This is considered a high-risk position. Responsibilities: We are seeking a talented and motivated individual keen...

  • Staff Scientist, Instrument Control Software

    23 hours ago

    San Jose, United States Thermo Fisher Scientific Full time

    Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving sophisticated analytical challenges, improving patient diagnostics and therapies or...

  • Staff Scientist, R&D

    1 day ago

    San Jose, United States Thermo Fisher Scientific Full time

    Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or...

  • Oligonucleotide Scientist-2

    2 weeks ago

    South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full time

    BEPC has an open position for an Oligonucleotide Scientist-2 in South San Francisco, CA!!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $39-$46/hr. + Medical, Dental, Vision and Life InsuranceWe are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our new oligonucleotide...

  • Oligonucleotide Scientist-2

    2 weeks ago

    South San Francisco, United States Kelly Science, Engineering, Technology & Telecom Full time

    Description:The Position:We are seeking a creative, self-motivated, collaborative Contractor/Scientist-II to join the Department of Protein Chemistry (PC) – ProteinSciences (PS). We are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our new oligonucleotide therapeutics discovery group. Experience in delivery...

  • Oligonucleotide Scientist-2

    2 weeks ago

    South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full time

    BEPC has an open position for an Oligonucleotide Scientist-2 in South San Francisco, CA!!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $39-$46/hr. + Medical, Dental, Vision and Life InsuranceWe are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our new oligonucleotide...

  • Oligonucleotide Scientist-2

    2 weeks ago

    South San Francisco, United States Kelly Science, Engineering, Technology & Telecom Full time

    Description:The Position:We are seeking a creative, self-motivated, collaborative Contractor/Scientist-II to join the Department of Protein Chemistry (PC) – ProteinSciences (PS). We are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our new oligonucleotide therapeutics discovery group. Experience in delivery...

  • Oligonucleotide Scientist-2

    2 weeks ago

    South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full time

    BEPC has an open position for an Oligonucleotide Scientist-2 in South San Francisco, CA!!Contract W2 Period: 12-month contract with possibilities for extensionsPay & Benefits: $39-$46/hr. + Medical, Dental, Vision and Life InsuranceWe are looking for a candidate with experience in oligonucleotide discovery and synthesis to support our new oligonucleotide...