Principal Scientist in Translational Medicine Mass Spectrometry

2 weeks ago


South San Francisco, United States The Fountain Group LLC Full time

Pay Range: $61-$101/hour

Job Description:

  • 12-month contract with the possibility of converting to permanent based on company needs and worker's performance.
  • The Translational Medicine department informs clinical development of Client personalized therapeutics through establishment of biomarker strategies aimed to study biological pathways driving disease and by characterizing the mechanism of action of Client therapeutics.
  • As a key member of the biomarker mass spectrometry laboratory, the ideal candidate will utilize mass spectrometry to explore Client biomarker hypotheses, assist in streamlining existing workflows, and help to drive innovation within the group through improved LC-MS/MS method development.
  • Experience in clinical proteomics and clinical sample processing is required. Hands-on experience with maintaining LC and MS instrumentation is also required.
Qualifications:
  • PhD in Analytical Chemistry, Biochemistry, or Biotechnology and successful postdoctoral research training in a related field
  • Minimum of 6 years of hands-on experience with liquid chromatography and tandem mass spectrometry (LC-MS/MS) approaches, and have excellent troubleshooting capabilities
  • Strong analytical background with fundamentals in assay development, system suitability, and method evaluation
  • Experience with discovery proteomics approaches (TMT, DIA-MS, SWATH, etc.) and corresponding data analysis tools
  • Knowledge of sample preparation techniques for analysis of biomarkers and other mediators from biological fluids (e.g. plasma, CSF, urine, stool, etc.)
  • A proven ability to analyze and visualize complex datasets using tools like MSstats, Spotfire, R, or Skyline and experience with standard instrument software such as Analyst or Xcalibur
  • In addition, the candidate should have excellent communication, presentation, and interpersonal skills, be able to work independently as well as in a team environment, and be willing and eager to learn and train others on new technologies.


  • South San Francisco, United States Compass Consulting Full time

    Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.  They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline. Job Overview: Our client's Translational...


  • South San Francisco, United States Compass Consulting Group Full time

    Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multi Spectrometry, Medicine, Scientist, Principal, Technology, Staffing


  • San Francisco, United States R&D Partners Full time

    R&D Partners is seeking to hire a Senior/ Principal Scientist in Translational Medicine Mass Spectrometry (Contractor) in San Franciscon, CA. Your main responsibilities as a Senior/ Principal Scientist in Translational Medicine Mass Spectrometry (Con Scientist, Principal, Clinical Research, Spectrometry, Chemistry, Staffing


  • South San Francisco, United States HonorVet Technologies Full time

    The Translational Medicine department at Genentech informs clinical development of Client personalized therapeutics through establishment of biomarker strategies aimed to study biological pathways driving disease and by characterizing the mechanism of action of Client therapeutics. As a key member of the biomarker mass spectrometry laboratory, the ideal...


  • South San Francisco, United States Parvus Therapeutics Full time

    Job DescriptionJob DescriptionParvus Therapeutics Inc. Parvus Therapeutics Inc. is a privately held biopharmaceutical company developing Navacims™, a platform technology based on foundational research published in 2016 (Nature 530:434), to treat autoimmune diseases. Parvus’ mission is to shift the treatment paradigm toward Navacim™-directed immune...


  • San Diego, CA, United States Kelly Services Full time

    Title: Mass Spectrometry Group LeaderLocation: San Diego, CA Work-Type: Direct-Hire, Full-Time, M-F 1st Shift + Option to WFH, per project loadSalary: $140K-160K (DOE) + Comprehensive Benefits + Relocation Support Job Description:As a Mass Spectrometry Group Leader, you will be involved in all client proteomics projects conducted in our laboratories, as well...


  • South San Francisco, California, United States Collabera Full time

    Operate and maintain analytical and preparative scale HPLC instrumentation.Purification of samples from medicinal chemistry projects on a milligram to gram scale by preparative HPLC.Maintain and troubleshoot NMR spectrometer under the guidance of senior scientists.Hands-on experience with analytical HPLC, preparative HPLC, mass spectrometry, and/or...


  • San Francisco, CA, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Data Scientist

    4 weeks ago


    San Francisco, California, United States Calico Full time

    Position Description:Calico is seeking an expert data scientist or computational biologist to join our multidisciplinary team of mass spectrometrists, biologists and computer scientists to become an integral part of our solution for proteomics.At Calico we are generating large quantities of proteomics data both from large, unique cohort studies as well as...

  • Principal Scientist

    7 days ago


    South San Francisco, United States Life Science People Full time

    Job Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...

  • Principal Scientist

    1 month ago


    South San Francisco, United States Life Science People Full time

    Job Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...

  • Principal Scientist

    34 minutes ago


    South San Francisco, United States Life Science People Full time

    Job Title: Senior Scientist/ Principal ScientistLocation: South San Francisco, CA Company Overview:Join a pioneering global biotech company at the forefront of cellular therapies, focusing on advanced dual-targeting CAR-T products. With a strong commitment to addressing unmet medical needs, backed by substantial financial support, my client is poised to...


  • San Francisco, California, United States University of California - San Francisco Full time

    The BCMM is focused on human microbiome research, with a particular interest in accelerating discovery and translation in the fields of early life microbiome and therapeutic development.The Center supports multiple collaborative technology hubs that facilitate microbiome research projects led by researchers across UCSF.Metabolomics: Sample preparation for...


  • San Diego, United States BioPhase Full time

    Sr. or Principal Scientist, Translational Genetics The ideal candidate will apply their background and experience in genetics, molecular biology and disease pathophysiology towards both identifying novel therapeutic targets and formulating mechanistic hypotheses that can be evaluated experimentally.Responsibilities:The Scientist will leverage extensive human...


  • San Diego, United States BioPhase Full time

    Sr. or Principal Scientist, Translational Genetics The ideal candidate will apply their background and experience in genetics, molecular biology and disease pathophysiology towards both identifying novel therapeutic targets and formulating mechanistic hypotheses that can be evaluated experimentally.Responsibilities:The Scientist will leverage extensive human...


  • San Diego, United States BioPhase Full time

    Sr. or Principal Scientist, Translational Genetics The ideal candidate will apply their background and experience in genetics, molecular biology and disease pathophysiology towards both identifying novel therapeutic targets and formulating mechanistic hypotheses that can be evaluated experimentally.Responsibilities:The Scientist will leverage extensive human...

  • Research Associate

    2 weeks ago


    South San Francisco, United States Aequor Technologies LLC Full time

    Job Title: Research Associate Location: South San Francisco, CA Duration: 1 year contract Note: The hiring manager's target would be for someone in level I-II, but they could stretch to level III depending on their experience and skill set. This is considered a high-risk position. Responsibilities: We are seeking a talented and motivated individual keen...


  • South San Francisco, United States Collabera Full time

    Job DescriptionJob DescriptionOperate and maintain analytical and preparative scale HPLC instrumentation.Support and troubleshoot walk-up analytical LC-MS instrumentation.Purification of samples from medicinal chemistry projects on a milligram to gram scale by preparative HPLC.Maintain and troubleshoot NMR spectrometer under the guidance of senior...

  • Postdoctoral Fellow

    1 month ago


    South San Francisco, United States Genentech, Inc Full time

    The Translational Medicine (TM) department at Genentech is seeking a highly motivated Postdoctoral Fellow (Bioinformatics) to lead analysis of complex biological datasets related to Neuroimmunology and Multiple Sclerosis. Our department provides translational science expertise to inform the clinical development of novel personalized therapeutics, and our...

  • Principal Scientist

    4 weeks ago


    San Diego, United States BioTalent Full time

    BioTalent has partnered with a biotechnology business based in San Diego who are looking for a Principal Scientist with a focus on proteomics.This is an ideal position for an expert in proteomics that is keen to work within an innovative organisation with potential to grow into a line management role.Responsibilities:Develop and implement innovative...