Upstream Process Development Scientist
4 weeks ago
Responsibilities
\t- Independently perform routine suspension cell culture (sampling, cell counting, passaging)
\t - Independently maintains and manages upstream equipment appropriately
\t - Support upstream technology strategies in various platforms including shakes flasks, rocker, 2L, 3L, 10L, and 50L from the development stage, tech transfer, engineering runs, and GMP manufacturing ; Assist in and execute unit operations for development, toxicology, and GMP batches for viral vector production(s).
\t - Contributes to continuous improvement strategies by designing experiments and presentation of results to internal and external stakeholders; evaluation of new technologies and collaboration with vendors
\t - Independent execution in the preparation of buffers/reagents ,bioreactor set-up (bench-top to 50L SUB), and sampling operations, monitoring of process performance, as well as cleaning and waste disposal to support process development operations.
\t - Ensuring adequate and appropriate inventory of materials and supplies, collaboration with supply chain, ordering materials
\t - Draft, edit, and/or review data capture forms, batch production records, standard operating procedures or standard work elements for process development equipment and/or unit operations.
\t - Maintain responsible laboratory protocols, data capture, lab notebooks, and/or files using GDP
\t - Collaborates with pre-clinical, analytical development, quality control, and manufacturing on the planning of upstream process development project timelines
Education and Experience
\t- BSc in a Biological Science/ Chemistry/ Chemical Engineering
\t - Expertise in AAV gene therapy
\t - Experience in and understanding of operations within a biosafety cabinet, cell culture incubators, cell culture shaking platforms, centrifugation equipment, aseptic technique, and associated general cleaning procedures
\t - Experience with media preparations, monitoring cell culture, routine sampling, preparation, execution, and analysis of cell expansion
\t - Handling various sized shake flasks and small-scale bioreactors in a process development setting
\t - Experience using MS Office, Excel and basic cell kinetic analysis
\t - Large-scale bioreactor experience is a plus
\t - AAV bioprocessing and development is a plus
\t - Experience with cell line development is a plus
\t - Experience in a GMP environment is a plus
Job Details
\t- Direct hire
\t - Schedule: Monday-Friday, day shift
\t - Pay rate dependent upon level of education and experience
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\t\t\t\tAs part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
Why Kelly® Science & Clinical?
Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world’s most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals—it’s the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.\t\t\t
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About Kelly
Work changes everything. And at Kelly, we’re obsessed with where it can take you. To us, it’s about more than simply accepting your next job opportunity. It’s the fuel that powers every next step of your life. It’s the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life—just ask the 300,000 people we employ each year.Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly’s Human Resource Knowledge Center.
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