Associate Researcher

4 weeks ago


Emeryville, United States Planet Pharma Full time

Research Associate- Protein Sciences

Emeryville, CA - ONSITE

SHIFT - MON-FRI 8AM-4:30PM

Position Summary:

We are seeking a Research Associate who will be responsible for the production and purification of antibodies and related therapeutic proteins. This position is based in Emeryville, CA, easily accessible by BART / EmeryGoRound, AMTRAK, or car (with private, secured, on-site parking provided.)

We have developed a proprietary approach for site-specific bioconjugation to produce next-generation ADCs. This technology, termed SMARTag, is based on use of the aldehyde-tag site-specific protein modification technology and our novel conjugation chemistry and proprietary, stable linkers. SMARTag is a clinical-stage technology, with its first ADC-TRPH-222-in Phase 1 clinical trials.

The site comprises a close-knit team of scientists working cross-functionally with each other to nimbly achieve our goals and milestones. We are a research site, working to develop therapeutic ADC drug candidates for clinical testing. We also continuously strive to improve and expand our technology platform. The team has a focus on publishing results and contributing to the exciting and dynamic field of bioconjugation and drug conjugates.

Key Competencies

  • Hands-on experience with cloning, mammalian cell cultures and aseptic techniques are required.
  • Cloning (Gibson assembly), Mini, Maxi, Giga preps, DNA sequence confirmation
  • Support the protein production by small- and large-scale transient transfection.
  • Experience with Vi-CELL , Octet and HPLC is required.
  • Experience in protein characterization assays such as concentration, endotoxin measurement, SDS-PAGE and SEC-HPLC is required.
  • Experience in antibodies and other protein purification techniques is preferred.
  • Experience using AKTA instruments is preferred.

Requirements

  • BS in biology, biochemistry, or a related discipline. BS with 0+ years of relevant experience.
  • 1 year of experience in a research lab environment, preferably including work under sterile conditions

Personal Characteristics

The successful candidate must possess the following characteristics:

  • A high degree of personal and professional integrity
  • Strong interpersonal and communication skills
  • Ability to deliver high quality results
  • Thrives in a fast-paced environment
  • Can adjust to changing situations, providing ideas and solutions

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