Head of Oligonucleotide Biology

2 weeks ago

Cambridge, United States ???? Full time

Simcere Pharmaceutical Group is a pharmaceutical company driven by innovative R&D. We are committed to 'Providing Today's Patients with Medicines of the Future ' across the following core therapeutic areas: oncology, central nervous system disorders, autoimmunity and infectious diseases. Meanwhile, we are also actively expanding our presence in disease areas with significant unmet medical needs in the future. The Boston Innovation Center was established by Simcere Pharmaceutical Group to develop ground-breaking technologies and transformative medicines in the field of oncology, CNS disorders, and autoimmune diseases.

We are seeking individuals who are collaborative, thrive in a fun and exciting culture, and are committed to advance cutting-edge neuroscience therapies to impact patients lives. This Senior/Executive Director position is based in Cambridge, MA, reporting to the VP of CNS Discovery. The ideal candidate will possess a proven track record in advancing groundbreaking modalities for the treatment of CNS diseases.

Responsibilities:

  • Lead the identification and mechanistic profiling and optimization of lead oligonucleotide compounds to provide high-value programs in line with Simcere's portfolio strategy.
  • Make strategic and quality decisions for the programs in alignment with Simceres management teams.
  • Be responsible for crafting an innovative product profile and guiding decision-making by formulating outcome scenarios at critical data inflection points.
  • Hold accountability for assembling and maintaining a motivated and high-performing program team, ensuring team members meet their expectations.
  • Provide relevant input into other portfolio project teams when needed.
  • Establish and cultivate cross-functional relationships with internal stakeholders.
  • Provide oversight to collaborative programs and maintain strong relationships with investigators and key opinion leaders (KOLs) in the field, both nationally and internationally.

Requirements

Qualifications:

  • PhD, MD or MD/PhD in neuroscience or related fields, with 6+ years of experience in oligonucleotide biology
  • Must have experience in leading a group to study RNA biology and function in academic or industrial settings.
  • Expertise in RNA therapeutic drug development process is highly desirable
  • Excellent communication and negotiation abilities, along with prior experience in leading organizations and guiding individuals through transformative changes
  • Demonstrated success in building teams, leading and influencing experienced professionals and executives
  • Ability to think critically, creatively and to anticipate and solve problems

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