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Sr. Scientific Specialist, Process Development

2 months ago

Boston, United States Ehub Global Inc Full time

Title: Sr. Scientific Specialist, Process Development

Location: Boston, MA 100% Onsite

Duration: 12+ Months

  • Stem-cell culture experience is a MUST
  • Upstream experience is a MUST


Key Responsibilities:

  • Oversee and perform routine stem cell culture, expansion, and differentiation of pluripotent stem cells to aid in process development, enhancement, and evaluation.
  • Establish and maintain laboratory capabilities for generating cell therapy process intermediates, as well as Drug Substance (DS) and Drug Product (DP) materials, adhering to predefined protocols.
  • Project Management: Oversee project timelines and deliverables, engage in complex troubleshooting, and perform Root Cause Analysis (RCA) as needed.
  • Documentation and Analysis: Accurately record experimental methods and outcomes in compliance with set standards. Analyze experimental data statistically to identify the trends, critical process parameters.
  • Collaboration: Work cohesively with internal teams to support departmental objectives. Play an active role in a multidisciplinary setting to meet collective targets.
  • Resource Coordination: Allocate resources and establish priorities for the team, contributing significantly to the department’s overarching objectives.


Requirements:

  • This role requires a high level of expertise in stem cell biology, process engineering, and project management, ensuring the successful development and implementation of cell therapy manufacturing processes.
  • A bachelor’s degree in Biochemistry, Engineering, Biology, or a related field with over 5 years of industry experience, or a Master’s degree with over 3 years of experience.
  • Capable of designing and conducting cell therapy experiments for process enhancement, including routine cell passaging and expansion in both adherent and suspension cultures in bioreactors independently.
  • Hands-on experience in aseptic techniques, Bioreactors, harvest & filtration operation
  • Flexibility: Availability for weekend work to maintain cell culture activities