Cryo-Electron Microscopy Specialist

3 months ago

Bethesda, United States Astrix Full time

Roles / Responsibilities

  • Perform sample preparation for both single-particle analysis (SPA) cryo-EM and cryo-electron tomography (cryo-ET).
  • Collect, analyze, and interpret cryo-EM and cryo-ET dataset.
  • Collaborate with other scientists to design and execute experiments.
  • Support the lab with operation of side-entry cold-holder
  • Train and mentor junior staff and scientists in cryo-EM and cryo-ET techniques.
  • Work with staff to conduct research, including planning and conducting experiments and data analysis.
  • Locate and review the literature pertinent to projects to identify the most applicable protocols and methods; perform experiments in accordance with protocols.
  • Collect, organize, and record experimental data for publication and future reference by others.
  • Prepare analyses and reports for publication and presentation; participate in laboratory meetings.
  • Organize and maintain laboratory, including inventory and ordering of supplies and equipment; organize and maintain stocks of reagents.
  • Provide orientation and training to new staff.
  • Provide training and mentoring to trainees and colleagues when needed.
  • Prepare datasets for publication and deposit in controlled-access databases.


Requirements

  • Bachelor’s degree; preference for MSc/Ph.D. degree in Biological Sciences or other related discipline.
  • Minimum of two years of experience in a research laboratory environment.
  • Minimum of 2 years of experience in the cryoEM field.
  • Experience with sample preparation for both SPA and Cryo-ET.
  • Experience in computational analysis of cryo-EM data
  • Familiarity with state-of-the-art cryo-EM software packages and high-performance computing units (HPC).
  • Current working knowledge of the software and hardware developments in cryo-EM, and limitations of the technique.
  • Interest in participating in research projects.
  • Strong communication skills, both oral and written.
  • Excellent analytical, organizational and time management skills.
  • Strong analytical and problem-solving skills.
  • Excellent communication and teamwork skills.


*******top of the range candidates should also have experience with computational analysis of CryoEM data.*******

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