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Automation Specialist

1 month ago

San Diego, United States SPECTRAFORCE Full time

Job Title: Automation Specialist / Associate Scientist - Automation

Duration: 12 Months

Location: San Diego, CA, 92121* Onsite


Job Description:

Actively seeking a highly skilled automation specialist with a strong background in liquid handling robotics and integration with supporting instrumentation. The ideal candidate will demonstrate innovative approaches when designing, optimizing, and implementing Next-Generation Sequencing (NGS) or cell- and organoid-based workflows on automated robotic systems. As part of this role, the candidate will cultivate a growth mindset and develop expertise in emerging automation technologies. The candidate will also conduct experiments, including scale-down, high-throughput, and automation, to enhance our team’s screening capabilities in patient-derived organoid model systems for early drug target discovery. This role offers a unique opportunity for the successful candidate to collaborate with diverse cross-functional scientific teams and contribute to groundbreaking drug discoveries that directly impact patient health.


Responsibilities:

• Integrate Liquid Handling Robotics: Seamlessly incorporate liquid handling robotics (such as Beckman-Coulter Biomek i7 & Dynamic Devices Lynx) with supporting instrumentation to execute molecular and cellular biology and organoid workflows.

• Automate Standardized Assays: Validate and deploy automated workflows for various standardized assays, including DNA/RNA purification, NGS library preparation, qPCR, cell and organoid passaging, cell/organoid media changes, cell-based viability assays, high-content cell imaging, and sample normalization.

• Collaborate and Translate Benchtop Processes: Work closely with scientists to translate benchtop processes into fully automated workflows. This involves programming/scripting stepwise protocols and rigorously validating processes through dry and wet runs.

• Design User-Friendly Processes: Develop and validate end-to-end processes on integrated lab automation platforms, prioritizing user-friendly design, robust execution, and secure data management.

• Troubleshoot and Enhance Efficiency: Perform advanced experimental troubleshooting alongside scientists to improve ease-of-use, process efficiency, and scientific integrity.

• Cross-Functional Collaboration: Collaborate with cross-functional teams to integrate NGS and organoid workflows into automated liquid handling systems, ensuring project success.

• Technical Troubleshooting: Address technical and instrument issues related to automation, NGS, and cell-based workflows.

• User Training: Train end-users in automated platform usage (Beckman-Coulter Biomek i7, Dynamic Devices Lynx, Analytik Jena CyBio FeliX) and workflow execution.

• Stay Current with Technology: Keep up-to-date with advancements in automation technology and emerging methodologies applicable to liquid handling systems.

• Independent Workflow Development: Work independently on novel automated workflows.

• Meticulous Record Keeping: Generate, organize, and maintain meticulous records of all conducted experiments.

• Collaboration and Organization: Collaborate with multiple teams across the organization, supporting and sharing methodologies while aligning efforts and harmonizing experimentation.

• Lab and Equipment Management: Manage lab and equipment organization and maintenance


Qualifications, Skills/Knowledge preferred:

• Master’s degree with 1+ year or Bachelor’s degree with 3+ years’ experience in bioengineering or biology with a strong focus on automation platforms & liquid handlers in pharmaceutical, biotechnology companies, or academic/not-for-profit organizations

• Minimum 3 years of hands-on experience programming and troubleshooting liquid handling platforms for high-throughput screening (HTS), as well as NGS- and organoid- or cell-based workflows

• Direct experience with laboratory operations and maintenance of common automation instruments used for NGS workflows

• Strong understanding of molecular and cellular biology, including NGS assays (e.g., DNA-seq, RNA-Seq). Demonstrated utilization of these assays in practical settings.

• Proven ability to create, follow, and maintain Installation Qualifications (IQ), Operational Qualifications (OQ), Performance Qualifications (PQ) protocols as well as Standard Operating Procedures (SOPs) for lab automation systems

• Successfully worked with R&D teams to deliver automation projects

• Effective communication and collaboration skills within a multidisciplinary team environment

• Functional knowledge of at least one high-level programming language (e.g., Python). Additional knowledge in other programming languages (e.g., Perl, R, C++) is a plus

• Experience programming, executing, and troubleshooting workflows using Beckman-Coulter and/or Dynamic Devices liquid handling platforms

• Proficient at organizing multiple concurrent projects and tasks.

• Excellent troubleshooting and problem-solving skills

• Rigorous and constant evaluation of own work to maintain high quality


Preferred Skills:

• Extensive hands-on experience with high-throughput methods, liquid handlers, and laboratory automation schedulers

• Proficiency in integrating liquid handling systems with supporting instrumentation

• In-depth expertise of end-to-end NGS workflows, with a focus on instrumentation and automation

• Functional understanding of cellular biology, molecular biology, DNA/RNA purification

• Proficiency in Next-Generation Sequencing (NGS) protocols

• Knowledge of automation programming and/or scripting (e.g., Python) for liquid handlers

• Previous experience in manual or automated organoid culture and assay development, is a plus


Additional Job Requirements?:

Lab w/ blood & animal

Position Handles Hazardous Materials


About Us: Established in 2004, SPECTRAFORCE® is one of the largest and fastest-growing diversity-owned staffing firms in the US. The growth of our company is a direct result of our global client service delivery model that is powered by our state-of-the-art A.I. proprietary talent acquisition platform, robust ISO 9001:2015/ISO 27001 certified processes, and strong and passionate client engaged teams. We have built our business by providing talent and project-based solutions, including Contingent, Permanent, and Statement of Work (SOW) services to over 140 clients in the US, Canada, Puerto Rico, Costa Rica, and India. Key industries that we service include Technology, Financial Services, Life Sciences, Healthcare, Telecom, Retail, Utilities and Transportation. SPECTRAFORCE is built on a concept of “human connection,” defined by our branding attitude of NEWJOBPHORIA®, which is the excitement of bringing joy and freedom to the work lifestyle so our people and clients can reach their highest potential. Learn more at:

Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.


Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.



At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $40.00/hr.