Bioinformatician/Computational Analyst or Sr Bioinformatician/Computational Analyst, The Robert M. Berne Cardiovascular Research Center

3 months ago

Charlottesville, United States Commonwealth of Virginia Full time
The Robert M. Berne Cardiovascular Research Center, at the University of Virginia is seeking a Bioinformatician/Computational Analyst or Sr Bioinformatician/Computational Analyst. The selected applicant will be part of a multidisciplinary team developing integrative analysis and machine learning/AI computational pipelines and performing analyses in collaborative projects using human multi-omic immune cell data, advanced imaging, genetic and clinical data as well as data from mouse model systems.

Candidate will identify opportunities and implement solutions for managing, visualizing, analyzing, and interpreting genomic, proteomic, single cell and spatial transcriptomic data. The successful candidate will have a demonstrated ability to translate biological questions into technical design, and to identify, prioritize, and execute bioinformatics tasks to meet project goals and deadlines. The analyst will participate in meetings and consultations with CVRC Researchers to discuss design and interpretation and will assist in manuscript and grant preparation. The candidate should have a passion for bioinformatics and enjoy collaborating and supporting academic researchers, attending seminars and meetings. The selected candidate will get an opportunity to master their bioinformatics skill set in a very close and interactive environment.

We seek a candidate that has strong communication skills and is a team player. A working knowledge of UNIX and scripting is important for this position. The ideal candidate is expected to have a good command of at least one language (C/C++ or R or Python). Knowledge of database development is a plus.

New PhD candidates are encouraged to apply for this position.

The successful candidate will be responsible for:
Organizing and managing large-scale sequencing data sets including single cell, and spatial transcriptomic data
Manipulating and formatting data with python, perl, UNIX tools
Using established open-source software and tools to assess quality and analyze data
Running analyses on a high-performance computing cluster
Using Unix or a scripting language to extract meaningful results from output
Using software or genome browsers for visualization
Using established databases and techniques for annotating genetic variants and results from expression/epigenetics experiments
Consulting with CVRC investigators on experimental design, result interpretation, and grant and manuscript preparation

Minimum Requirements

Bioinformatician /Computational Analyst

Education: Master's degree in Statistics, Data Science, Physics, Mathematics, Biophysics, Engineering, Chemistry science or a related field.

Experience:
Strong knowledge working in a Unix/Linux environment and experience with high-performance computing.
Advanced proficiency with R/Bioconductor or Python or C/C++.
Experience with open-source software, tools, and databases for analyzing next-generation sequencing data (RNA-seq, ChIP-seq, ATAC-Seq, DNA variation, epigenetics, microbiome, metagenomics etc.).
Excellent teamwork, communication and writing skills.
Knowledge of molecular and cellular biology concepts is preferred

Sr Bioinformatician /Computational Analyst

Education: Master's degree in Bioinformatics, Genomics, Biostatistics, Computer science or a related field. PhD in related field preferred.

Experience:
Minimum of 5 years of experience with programming in Python and R with a strong background in UNIX is preferred.
Strong knowledge working in a Unix/Linux environment and experience with high-performance computing.
Advanced proficiency with R/Bioconductor or Python or C/C++.
Candidates with extensive experience in development of computational pipelines and large-scale data management are highly encouraged to apply.
Experience with open-source software, tools, and databases for analyzing next-generation sequencing data (RNA-seq, ChIP-seq, ATAC-Seq, DNA variation, epigenetics, microbiome, metagenomics etc.).
Excellent teamwork, communication and writing skills.
Knowledge of molecular and cellular biology concepts is preferred
Preference given to those with formal training in integrative and/or machine learning analysis of single cell and bulk RNAseq, mass cytometry, spatial transcriptomics, functional genomics, and biomedical data.

This is a restricted position; continuation is dependent on funding and satisfactory performance.

This position is located in Charlottesville, Virginia. This is a full-time benefited position. For more information on the benefits at UVA, visit www.hr.virginia.edu/benefits .

The anticipated hiring range is commensurate with education and experience. The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.

To Apply: Please apply through the UVA job board , and search for R0061084. Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs'. Complete an application online with the following documents:
• CV/Resume
• Cover letter

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.

The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.

For questions about the application process, please contact Jon Freeman, Recruiting Specialist, at

For more information about UVA and the Charlottesville community, please see and .

Physical demands: This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.

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