Senior Scientist I, Purification
2 months ago
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description
A Senior Scientist position is available within the Purification Process Development group in PD S&T Biologics. This role will be located at either the AbbVie Bioresearch Center in Worcester, MA or the Antibody Drug Conjugate Center of Excellence in Waltham, MA. The group is responsible for developing downstream purification processes for early and late phase clinical programs. The ideal candidate will conceive and implement novel experimental and/or modeling approaches to answer scientific questions. The mission of this team is to address challenging problems in biologics development areas by working collaboratively and cross-functionally by developing appropriate tools and technologies to enable right at first pass scale-up and technology transfer of various biologics modalities drug substance processes.
Key Responsibilities:
Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bispecifics, and antibody drug conjugates (ADC).Design and execute process development and characterization activities, impurity and viral clearance studies.Provide deeper understanding of process performance using appropriate experimental and modeling tools.Proactively seek opportunities and new information to come up with innovative solutions to challenging business problems through creative solutions.Responsible for technology transfer to pilot lab and cGMP manufacturing facilities, troubleshooting and investigation activities.Critically evaluate relevant scientific, regulatory and business advances and integrate this knowledge.Effectively communicate scientific data and concepts to internal and external audiences through reports, presentations and manuscripts. Author and review technical reports, protocols, and other key documents.Understand and adhere to corporate standards regarding code of conduct, safety, documentation and GMP compliance.Qualifications
Bachelors degree or equivalent education and typically 10 years of experience, Masters degree and typically 8 years of experience, PhD degree and 0-2 years of experience.Education background in chemical engineering, biomedical engineering, biochemistry, biochemical engineering, or biotechnology is preferred.Experience in areas of purification process development is preferred.Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications.Seamlessly present research outcomes to multifunctional teamsBe a strong team player in a cross functional, collaborative environment thriving for world class excellence and maintains strong working relationships with internal, global, and external collaborators.Demonstrated problem-solving skills and capability to overcome complex issues.Demonstrated success in coordinating and executing important projects to achieve business goals.Must have a results-oriented work ethic and a positive can-do attitude with a strong sense of urgency and self-motivated desire to achieve.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit
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