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Senior Scientist II, Pathology
3 months ago
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description
We are seeking a highly motivated individual to work within the Precision Medicine Pathology Group to develop and implement tissue-based assays to support drug development in oncology and other therapeutic areas. The Senior Scientist will drive the design, implementation and analysis of diagnostic and translational tissue-based biomarkers & participate in target discovery and validation projects.
This role will accomplish this by conducting histopathological evaluation as well as computer-based image analysis of IHC and other tissue-based assays, as well as by providing technical/scientific leadership in these areas.
The successful candidate will have the opportunity to work in a highly collaborative environment and will participate as a member of multidisciplinary, cross-functional discovery, translational, and development project teams.
Major Responsibilities
Design, validate, and implement histochemical, IHC, and IF staining using Leica Autostainer XL, Ventana Discovery ULTRA, and Leica BOND RX platform.Perform routine histological procedures including tissue accessioning, gross-dissection, tissue processing, embedding, sectioning, staining and image capture of frozen and FFPE tissuesPerform image capture (whole slide scanning), data entry and organizationPerform image analysis using HALO and Visiopharm technologiesGenerate data and present findings to relevant project teams in departmental and cross-functional meetingsLead and maintain external vendor collaborations and relationshipsTrain staff in image analysis, quantification, and spacial biology techniquesEvaluate and bring in new and innovative image analysis and spacial biology tools and techniquesQualifications
Bachelors Degree in Science related field with 15+ years of related work; Masters Degree Science with 10+ years of related work; PhD in Science or related field* with 4+ years of related work experience. (*Cancer Biology, Physiology, Cell Biology or a related field)Strong familiarity with the principles of tissue microscopic anatomy/histologyExperience working in collaboration with trained pathologistsHands-on experience with development of immunohistochemistry (IHC) and other tissue-based assays including immunofluorescence (IF) multiplexing and in situ hybridization (ISH) preferredExpertise in quantitative image analysis software and its application to IHC and other tissue-based staining modalitiesExcellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. This job is eligible to participate in our long-term incentiveprograms Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit
