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Principal Research Scientist I

4 months ago

Irvine, Kentucky, United States AbbVie Full time

Company Description

At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit Follow Allergan Aesthetics on LinkedIn.
Job Description

Allergan Aesthetics Biological Research is seeking a highly motivated and innovative candidate who will direct and contribute to multi-disciplinary research in a highly collaborative environment. The successful candidate will lead a team performing in vivo pharmacological research to characterize existing and novel toxin protein therapeutics. She/He/They will be responsible for managing a team of in vivo scientists to design and perform pharmacology studies using existing and novel assays aimed at evaluating the effects of botulinum neurotoxins on muscle paralysis. The ideal candidate will be a recognized leader and technical expert in the field who will investigate, identify, develop and optimize new methods/techniques to address critical project needs.

The ideal candidate will have a strong and established background in pharmacology, specializing in in vivo pharmacology, and a proven track record of successfully leading diverse and matrixed project teams to drive novel therapeutics into development. The candidate will have experience with project conception, strategic planning, analysis, interpretation of results, come forward with recommendations, or understanding of the results, communicate and present at team meetings and in reports, and have exceptional troubleshooting skills. Additionally, the candidate will have a strong working knowledge in several research areas including neuroscience, rodent anatomy, and histology. The candidate will be able to lead by influence and maintain a productive, collaborative, and inclusive laboratory environment in compliance with regulatory and company expectations.

Key responsibilities:

Drive functional performance by leading team members in designing and performing in vivo assays, and analyzing pharmacological results to answer scientific questions.

Set functional goals with experimental timelines and execute a strategy in alignment with the goals and key scientific objectives for the research.

Demonstrate creative out of the box thinking to solve difficult problems, champion new technologies, and independently modify experimental plans when required to achieve project goals.

Understand the broad objectives of the project as well as their role in achieving those objectives.

Work with cross-functional team members to accomplish the goals and requirements of the organization.

Make significant contributions to project teams through lab-based, or other work environment activities.

Manage project activities and professional development of a team of scientists through effective mentoring, guidance, and supervision.

Advance scientific expertise within the function and collaborate with cross-disciplinary teams to help advance programs from research to development.

Perform data analysis, write scientific reports, and provide presentations to multidisciplinary teams and to management.

Demonstrate a high level of proficiency and expertise in his/her discipline.

Learn, understand, and master new experimental techniques, and act as a resource, mentor and leader of others.

Maintain awareness of emerging literature and science in the neurotoxin field and help author scientific disclosures, as needed.

Contribute to writing regulatory documents in compliance with Federal Regulations, including protocols, study reports, relevant sections of investigator brochures and INDs, white papers, patents and other similar documents.

Effectively organize and present program updates and research strategies to functional and non-functional leaders as well as potential and existing partners.

Provide expert advice and share knowledge with direct reports, peers, and senior management.

Provide guidance to develop both the skills and the careers of direct reports.

Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, and radioactive compounds, GxP compliance, and animal care where applicable.


Qualifications

Job Qualifications (minimum requirements):

Extensive experience with pharmacological assays, focusing on in vivo pharmacology in an industrial research environment, with at least 6+ years of experience managing teams and cross-functional projects.

Direct experience with peripheral animal models and measurements is an big advantage.

Strong knowledge and experience in neuroscience, both central and peripheral, animal anatomy and histological assays and methods.

Extremely organized and experienced with documentation of experimental plans, timelines, and technical reports.

Experience in authoring or contributing to technical reports and regulatory documents.

Highly organized and self-directed, capable of leading multiple complex research programs in parallel.

Solid understanding of standard statistical analysis of scientific data using data software tools (e.g., Prism, SigmaPlot, and SPSS).

Detailed oriented and precise in written and oral communication.

Effective problem solving skills.

Ability to critically analyze data and lead teams to solve issues and make best strategic decisions.

Highly collaborative, team-oriented, and considerate of the needs of others.

Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners.

Proven team leadership and management abilities, including experience mentoring, guiding, supervising, and developing scientific personnel with various backgrounds and training levels.

Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued; willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view.

Education & Experience:

PhD in Biology, Pharmacology, Neuroscience, Biochemistry, or equivalent field with 6+ years of experience in in biotech or pharma; Masters Degree or PharmD with 12+ years of experience will also be considered.


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.This job is eligible to participate in our short-term incentive programs. This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion, consistent with applicable law. AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.