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Associate Scientist/Scientist

3 months ago

Irvine, United States Aureka Biotechnologies, Inc. Full time

Position: Associate Scientist – Scientist I

Location: Laguna Hills, CA

Company: Aureka Biotechnologies

Job Type: Full-Time

Reports To: Director

 

About Us:

Aureka Biotechnologies is an innovative startup focused on AI-driven antibody design to revolutionize drug development. We are a dynamic team dedicated to advancing scientific research and bringing transformative therapies to market. As a small but growing company, we offer a collaborative environment where every team member's contribution is crucial to our success.

 

Job Summary:

We are seeking an outstanding scientist with a broad range of skills to support the antibody drug discovery from our proprietary antibody discovery and engineering platforms. The successful candidate will be a highly motivated team player and be able to multitask in an exciting, fast-paced environment. This position offers an exciting opportunity to gain hands-on experience in antibody screening and characterization while contributing to cutting-edge scientific discoveries.

 

Key Responsibilities:

  • Antibody Construction & Characterization: Antibody library construction, antibody screening utilizing flow cytometry, ELISA, and cell-based functional assays.
  • Antibody Expression: such as cell-free systems
  • Cell Line Maintenance: Yeast/mammalian cell lines for cell-based assays, reagent preparation, and inventory. 
  • Data Analysis: Analyze and interpret experimental data, prepare detailed reports, and present findings to the research team and senior management.
  • Experimental Design: Collaborate with team members to design and implement experiments aligned with project goals and timelines.
  • Documentation: Maintain accurate and detailed laboratory records in Benchling in accordance with company policies.
  • Team Collaboration: Work closely with cross-functional teams, including computational biologists, engineers, business development, and project managers, to drive research projects forward.
  • Innovation: Stay current with the latest scientific literature and technological advancements to bring innovative ideas and techniques to the team.

 

Qualifications:

  • Preferred Experience: MS or Ph.D in Biological Sciences, Biochemistry, Molecular Biology, Immunology, Biopharmaceutical, or related field with 4+ (MS) and 1+ (Ph.D) years of relevant industry experience.
  • Previous laboratory experience in molecular biology, cell culture, and protein biochemistry techniques is desirable.
  • Technical Skills:
  • Vector construction for transgene expression in mammalian cells, reporter gene-based assay development and qualification.
  • Antibody screening and selection techniques, such as phage/yeast/mammalian cell display, hybridoma, and ribosome display.
  • Any high throughput screening platform experience for ranking protein’s biophysical properties or binding affinities through biochemistry or cell-based essay.
  • Any single-cell technology experience for RNA or functional analysis combined with next-generation sequencing (NGS).
  • Soft Skills:
  • Excellent communication skills, with the ability to work effectively in a collaborative team environment
  • Strong organizational and time-management abilities
  • Strong analytical and problem-solving skills, with the ability to troubleshoot experiments and optimize protocols independently.


Benefits:

  • Competitive salary and equity options
  • Comprehensive health, dental, and vision insurance
  • Professional development opportunities
  • Collaborative and inclusive company culture