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Scientist - AssayDev (R)

2 months ago


Andover, Massachusetts, United States Pfizer Full time
This position requires full time onsite in Andover, MA (no relocation available)

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best - in - class medicines to patients around the world.

What You Will Achieve

Pfizer Research and Development (PRD) at Pfizer combines research and technology units that have deep disease area expertise and cutting-edge science and platforms to discover and develop innovative therapeutic programs in small molecules and biotherapeutics, including vaccines. In your role, you will work under the guidance of a supervisor with high degree of independence and be responsible for the development and validation of robust and reliable ligand binding and cell-based assays suitable for biotherapeutics quantification and immunogenicity assessment in various biological matrices using a range of potential platforms and assay techniques. You will generate compound concentration and immunogenicity data in compliance of regulatory requirement. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members.

It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

Laboratory focused position. Knowledge and hands-on experience on developing ligand binding assay and cell-based assay, utilizing various platforms and assay techniques.
Design, develop and implement ligand binding assays (e.g. ELISA, ECL detection) to measure compound concentration in biological matrix (plasma, serum), detect the presence of anti-drug antibody and neutralizing anti-product antibody activity utilizing various platform in a regulated (GLP, GCP) environment against challenging timelines.
Timely delivery of concentration and immunogenicity data to a supervisor and other partners in compliance with local or global regulatory requirement.
Advance bioanalytical capabilities to improve efficiency, cost effectiveness and
appropriateness of assay for regulated support.

Qualifications

Must-Have

Bachelor's Degree and typically associated with 5 years of relevant GLP/GCP laboratory experience or Master's Degree with at least 3 years of relevant GLP/GCP laboratory experience, with a focus on ligand binding assay and/or cell-based assay development.
Proven track record in the area of biotherapeutics bioanalysis with understanding of a broad range of bioanalytical platforms.
Skills in GLP/GCP compliant analysis including following SOP and provision of quality regulatory documents.

Nice-to-Have

Industry experience with a focus in PK/immunogenicity assays and a strong record of scientific achievement.
Proven experience generating analytical data and analytical problem-solving skills in a regulated environment.
Ability to author technical documents like SOPs, data summary reports and analytical procedures.
Excellent communication and presentation skills and a proven track record of teamwork, adaptability, innovation, leadership and initiative.

PHYSICAL/MENTAL REQUIREMENTS

This position includes lifting, sitting, standing, walking, bending, and requires ability to perform mathematical calculations and complex data analysis.

Work Location Assignment:On Premise

The annual base salary for this position ranges from $74,900.00 to $124, In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | ). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

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