Program Director, RNA Therapeutics

3 weeks ago


Boston, Massachusetts, United States Ginkgo Bioworks, Inc Full time

The successful applicant will have a deep technical background in RNA biology and understands how to deploy various toolkits including cell engineering, genetics and functional genomics, NGS, and high-throughput screening approaches to design better RNA sequences that support long-term or tissue-specific translation.Expertise is required with how RNA secondary structure and topology affects both its generation ( in vitro or in vivo ) and its function.Knowledge of in vitro transcription methods for generating RNAs and familiarity with RNassociated immunogenicity is important.Please note: this role could be based in either our Seaport or Cambridge locations, but requires some flexibility to occasionally be present at the other location.PhD or equivalent experience in molecular biology, bioengineering, synthetic biology, or related fieldDirect experience and technical leadership in projects investigating RNA sequence-structure-function relationships in the context of translation, stability, catalysis, interference, or any other RNA process.Strong molecular biology expertise, with significant experience in mammalian cell culture and familiarity with next-generation sequencing technologiesDirect experience and technical leadership in generating and screening large libraries of RNA elements to elucidate sequence-structure-function relationships between those elements and RNA processes (ie catalysis, translation, stability, interference, etc)



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