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Downstream Process Development Scientist
4 months ago
Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. With associates across 40+ countries, Cytiva is a place where every day is a learning opportunity – so you can grow your career and expand your skills in the long term.
Forming part of the Biotechnology segment at Danaher, we bring together dedicated technical expertise and talent to develop the next generation of life-changing therapeutics.
The Downstream Process Development Scientist for Cytiva is responsible for supporting the Fast Trak Process Development Services (PDS) group by providing technical and scientific support for the execution of downstream PD and scale-up process for various biologics modalities.
This position is part of the Fast Trak Process Development Services located in Marlborough, MA and will be on-site. At Cytiva, our vision is, to advance future therapeutics from discovery to delivery.
What you will do:
- Be one of the primary technical points of contact within downstream PDS, responsible for SOP generation, investigations, and resolution of complex technical issues.
- Responsible for planning, and hands-on execution of downstream processes with in-depth knowledge of depth filtration clarification, chromatography, tangential flow filtration, and sterile filtration for a variety of biologics modalities (viral vectors, nucleic acids, mAbs). Document work and results in concise reports and provide project updates in written and oral presentations.
- Conduct risk assessments and technical investigations related to PD and scale-up processes.
- Contribute to a safe, efficient, and effective lab environment with personal accountability.
- Perform occasional extended hours, and other duties as assigned, to support ongoing lab activities.
Who you are:
- Bachelor's degree or higher in biochemical engineering, molecular biology, biochemistry, or related scientific subject area.
- 3+ years in process development or clinical manufacturing laboratory setting with a focus on downstream process development, process scale-up, and process tech transfer for biologics modalities.
- Possesses excellent bench skills with attention to detail and high standards for data integrity and quality.
- Proven record of successfully planning, executing, and reporting to meet project deliverables and timelines.
- Team player with ability to perform in a fast-paced environment with minimal supervision.
It would be a plus if you also possess previous experience in:
- Working knowledge of analytical assays is a great plus (ELISA, qPCR, gel electrophoresis, HPLC).
- Experience with nucleic acid process development supporting pDNA to mRNA workflows is highly desirable.
At Danaher we bring together science, technology and operational capabilities to accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. Our global teams are pioneering what's next across Life Sciences, Diagnostics, Biotechnology and beyond. For more information, visit
Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.
The EEO posters are available here.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at to request accommodation.
